Literature DB >> 18301932

The myth of lumbar instability: the importance of abnormal loading as a cause of low back pain.

R C Mulholland1.   

Abstract

Spinal fusion became what has been termed the "gold standard" for the treatment of mechanical low back pain, yet there was no scientific basis for this. Operations of fusion for low back pain were initially done at the beginning of the last century for back pain thought to be related to congenital abnormalities or for past spinal infection. The recognition of the disc as a cause of sciatica, commonly associated with back pain, and the recognition that a degenerate disc led to abnormal movement suggested the concept that this abnormal movement was the cause of pain, and this abnormal movement came to be called "instability". Much biomechanical expertise confirmed the fact that degenerate discs led to abnormal movement, there were many hypothesis as to why this caused pain. However clinical results of fusion for back pain were unpredictable. The failure of pedicle screws and cage fusion to improve the clinical results of fusion despite near 100% fusion success, and the introduction of "flexible stabilization" and artificial discs, which demonstrated that despite the often unpredictable movement permitted by of these devices, clinical success was similar to fusion, directed attention to the other role of the disc, that of load transfer, which these devices also affected. Abnormal load transfer was already known to be critical in other joints in the body and had led to the use of osteotomy to realign joints. The relevance of load transfer to the future design of spinal implants used in the treatment of low back pain is discussed, and some finite element studies are reported demonstrating the likely effect of abnormal loading beneath an incompletely incorporated plate of an artificial disc, perhaps explaining in part the somewhat disappointing clinical results to date of the implantation of artificial discs.

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Mesh:

Year:  2008        PMID: 18301932      PMCID: PMC2367421          DOI: 10.1007/s00586-008-0612-2

Source DB:  PubMed          Journal:  Eur Spine J        ISSN: 0940-6719            Impact factor:   3.134


  38 in total

1.  Structural changes in the lumbar intervertebral discs; their relationship to low back pain and sciatica.

Authors:  R I HARRIS; I MACNAB
Journal:  J Bone Joint Surg Br       Date:  1954-05

2.  Analysis of stress distribution in lumbar interbody fusion.

Authors:  Naresh Kumar; Meakin R Judith; Aravind Kumar; Viren Mishra; Mulholland C Robert
Journal:  Spine (Phila Pa 1976)       Date:  2005-08-01       Impact factor: 3.468

Review 3.  Scientific basis for the treatment of low back pain.

Authors:  R C Mulholland
Journal:  Ann R Coll Surg Engl       Date:  2007-10       Impact factor: 1.891

4.  The implications of stress patterns in the vertebral body under axial support of an artificial implant.

Authors:  V Palissery; R C Mulholland; D S McNally
Journal:  Med Eng Phys       Date:  2009-05-05       Impact factor: 2.242

5.  Morphologic study of lumbar vertebral osteophytes.

Authors:  M H Heggeness; B J Doherty
Journal:  South Med J       Date:  1998-02       Impact factor: 0.954

6.  Tibial osteotomy in the management of osteoarthritis of the knee.

Authors:  W Waugh
Journal:  Clin Orthop Relat Res       Date:  1986-09       Impact factor: 4.176

7.  Tibial osteotomy for osteoarthritis of the knee.

Authors:  J P Jackson; W Waugh
Journal:  Acta Orthop Belg       Date:  1982 Jan-Feb       Impact factor: 0.500

8.  Loads on the lumbar spine. Validation of a biomechanical analysis by measurements of intradiscal pressures and myoelectric signals.

Authors:  A Schultz; G Andersson; R Ortengren; K Haderspeck; A Nachemson
Journal:  J Bone Joint Surg Am       Date:  1982-06       Impact factor: 5.284

9.  The effect of disc degeneration and facet joint osteoarthritis on the segmental flexibility of the lumbar spine.

Authors:  A Fujiwara; T H Lim; H S An; N Tanaka; C H Jeon; G B Andersson; V M Haughton
Journal:  Spine (Phila Pa 1976)       Date:  2000-12-01       Impact factor: 3.468

10.  Diagnosis of symptomatic disc by magnetic resonance imaging: T2-weighted and gadolinium-DTPA-enhanced T1-weighted magnetic resonance imaging.

Authors:  Hiroyuki Yoshida; Atsushi Fujiwara; Kazuya Tamai; Naoki Kobayashi; Kazuhiko Saiki; Koichi Saotome
Journal:  J Spinal Disord Tech       Date:  2002-06
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  16 in total

1.  Radiographic parameters of segmental instability in lumbar spine using kinetic MRI.

Authors:  Se Youn Jang; Min Ho Kong; Henry J Hymanson; Tae Kyung Jin; Kwan Young Song; Jeffrey C Wang
Journal:  J Korean Neurosurg Soc       Date:  2009-01-31

Review 2.  The Michel Benoist and Robert Mulholland yearly European Spine Journal Review: a survey of the "medical" articles in the European Spine Journal, 2010.

Authors:  Michel Benoist
Journal:  Eur Spine J       Date:  2011-01-08       Impact factor: 3.134

Review 3.  The Michel Benoist and Robert Mulholland yearly European Spine Journal Review: a survey of the "surgical research" articles in the European Spine Journal 2014.

Authors:  Robert C Mulholland
Journal:  Eur Spine J       Date:  2015-01-03       Impact factor: 3.134

Review 4.  The Michel Benoist and Robert Mulholland yearly European Spine Journal Review: a survey of the "surgical and research" articles in the European Spine Journal, 2016.

Authors:  Robert C Mulholland
Journal:  Eur Spine J       Date:  2017-01-06       Impact factor: 3.134

5.  The Michel Benoist and Robert Mulholland yearly European Spine Journal review: a survey of the "surgical and research" articles in the European Spine Journal, 2018.

Authors:  Robert C Mulholland
Journal:  Eur Spine J       Date:  2019-01-02       Impact factor: 3.134

6.  Mechanical role of the posterior column components in the cervical spine.

Authors:  Robert A Hartman; Robert E Tisherman; Cheng Wang; Kevin M Bell; Joon Y Lee; Gwendolyn A Sowa; James D Kang
Journal:  Eur Spine J       Date:  2016-04-06       Impact factor: 3.134

7.  Paraspinal Muscle Spindle Response to Intervertebral Fixation and Segmental Thrust Level During Spinal Manipulation in an Animal Model.

Authors:  William R Reed; Joel G Pickar
Journal:  Spine (Phila Pa 1976)       Date:  2015-07-01       Impact factor: 3.468

8.  Late infections after dynamic stabilization of the lumbar spine with Dynesys.

Authors:  Jon A Lutz; Philippe Otten; Gianluca Maestretti
Journal:  Eur Spine J       Date:  2012-05-19       Impact factor: 3.134

9.  A combined numerical and experimental technique for estimation of the forces and moments in the lumbar intervertebral disc.

Authors:  Shaobai Wang; Won Man Park; Hemanth R Gadikota; Jun Miao; Yoon Hyuk Kim; Kirkham B Wood; Guoan Li
Journal:  Comput Methods Biomech Biomed Engin       Date:  2012-05-03       Impact factor: 1.763

10.  In vivo preclinical evaluation of the influence of osteoporosis on the anchorage of different pedicle screw designs.

Authors:  Gianluca Giavaresi; Milena Fini; Roberto Giardino; Francesca Salamanna; Maria Sartori; Veronica Borsari; Silvia Spriano; Chiara M Bellini; Marco Brayda-Bruno
Journal:  Eur Spine J       Date:  2011-05-05       Impact factor: 3.134

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