| Literature DB >> 18298791 |
Jeroen den Hertog1, Arne Ostman, Frank-D Böhmer.
Abstract
Protein-tyrosine phosphatases are tightly controlled by various mechanisms, ranging from differential expression in specific cell types to restricted subcellular localization, limited proteolysis, post-translational modifications affecting intrinsic catalytic activity, ligand binding and dimerization. Here, we review the regulatory mechanisms found to control the classical protein-tyrosine phosphatases.Mesh：
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Year: 2008 PMID： 18298791 DOI： 10.1111/j.1742-4658.2008.06247.x
Source DB: PubMed Journal: FEBS J ISSN： 1742-464X Impact factor: 5.542