Literature DB >> 22311969

Novel Ser/Thr protein phosphatases in cell death regulation.

Haipeng Sun1, Yibin Wang.   

Abstract

Cell death is regulated by a myriad of intracellular molecular pathways, with many involving protein phosphorylation and dephosphorylation. In this review, we will focus on Ser/Thr phosphatases-mediated regulation in cell apoptosis as well as on their potential roles in cell necrosis. The emerging functional importance of Ser/Thr protein phosphatases in cell death regulation adds new dimension to the signaling mechanisms of cellular function, physiology, and diseases.

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Year:  2012        PMID： 22311969      PMCID： PMC3808828          DOI： 10.1152/physiol.00034.2011

Source DB:  PubMed          Journal:  Physiology (Bethesda)        ISSN： 1548-9221


  131 in total

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4.  RIP kinases initiate programmed necrosis.

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5.  Protein phosphatase 5 regulates the function of 53BP1 after neocarzinostatin-induced DNA damage.

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8.  Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation.

Authors:  Young Sik Cho; Sreerupa Challa; David Moquin; Ryan Genga; Tathagat Dutta Ray; Melissa Guildford; Francis Ka-Ming Chan
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9.  Functional complementation between FADD and RIP1 in embryos and lymphocytes.

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10.  Role of the mitochondrion in programmed necrosis.

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  7 in total

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2.  Mlkl knockout mice demonstrate the indispensable role of Mlkl in necroptosis.

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Review 3.  Cyclic Nucleotide-Directed Protein Kinases in Cardiovascular Inflammation and Growth.

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Review 5.  Metal dependent protein phosphatase PPM family in cardiac health and diseases.

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6.  Comprehensive Phosphoproteomic Analysis of Nostoc flagelliforme in Response to Dehydration Provides Insights into Plant ROS Signaling Transduction.

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Journal:  ACS Omega       Date:  2021-05-17

7.  β-Lapachone suppresses the lung metastasis of melanoma via the MAPK signaling pathway.

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Journal:  PLoS One       Date:  2017-05-08       Impact factor: 3.752
  7 in total

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