Literature DB >> 18291311

Targeting the bacterial Z-ring.

Waldemar Vollmer1.   

Abstract

FtsZ is a prokaryotic homolog of eukaryotic tubulin and forms the essential bacterial cell division ring (Z-ring). A new study in this issue of Chemistry & Biology, Läppchen et al., provides further evidence that differences in nucleotide-binding properties of FtsZ and tubulin can be exploited to specifically target the bacterial Z-ring.

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Year:  2008        PMID: 18291311     DOI: 10.1016/j.chembiol.2008.02.001

Source DB:  PubMed          Journal:  Chem Biol        ISSN: 1074-5521


  5 in total

1.  Practical synthesis of PC190723, an inhibitor of the bacterial cell division protein FtsZ.

Authors:  Nohemy A Sorto; Marilyn M Olmstead; Jared T Shaw
Journal:  J Org Chem       Date:  2010-10-29       Impact factor: 4.354

2.  Synthesis of antimicrobial natural products targeting FtsZ: (+)-totarol and related totarane diterpenes.

Authors:  Michelle B Kim; Jared T Shaw
Journal:  Org Lett       Date:  2010-08-06       Impact factor: 6.005

3.  Septal localization of the Mycobacterium tuberculosis MtrB sensor kinase promotes MtrA regulon expression.

Authors:  Renata Plocinska; Gorla Purushotham; Krishna Sarva; Indumathi S Vadrevu; Emmanuel V P Pandeeti; Naresh Arora; Przemyslaw Plocinski; Murty V Madiraju; Malini Rajagopalan
Journal:  J Biol Chem       Date:  2012-05-20       Impact factor: 5.157

4.  Transcriptional profiles of the response of methicillin-resistant Staphylococcus aureus to pentacyclic triterpenoids.

Authors:  Pooi Yin Chung; Lip Yong Chung; Parasakthi Navaratnam
Journal:  PLoS One       Date:  2013-02-20       Impact factor: 3.240

5.  Targeting the Wolbachia cell division protein FtsZ as a new approach for antifilarial therapy.

Authors:  Zhiru Li; Amanda L Garner; Christian Gloeckner; Kim D Janda; Clotilde K Carlow
Journal:  PLoS Negl Trop Dis       Date:  2011-11-29
  5 in total

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