Literature DB >> 1828965

Treatment of breast cancer in two teaching hospitals: a comparison with consensus guidelines.

M McCarthy1, J Bore.   

Abstract

We compared the initial treatment of 383 patients with breast cancer in two central London teaching hospitals during 1986 with the guidelines of the King's Fund Consensus Conference for breast cancer treatment held in London the same year. The majority of patients (68%) received lumpectomy and 18% received mastectomy. Lumpectomy was followed by radiotherapy for 95% of cases but 30% of mastectomy patients also received radiotherapy. Only 42% of the patients had surgical sampling of the axillary nodes. Cytotoxic chemotherapy was recorded for 27% women under 50, but also for 16% women age 50 or more. Tamoxifen was given to 58% of women aged 50 or more, but also to 26% of women under 50. We conclude that there are discrepancies between consensus guidelines and clinical practice. Further study is needed to determine whether these variations are clinically important, and whether similar variations exist elsewhere in Europe.

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Year:  1991        PMID: 1828965     DOI: 10.1016/0277-5379(91)90222-y

Source DB:  PubMed          Journal:  Eur J Cancer        ISSN: 0959-8049            Impact factor:   9.162


  11 in total

Review 1.  Tamoxifen: a review of pharmacoeconomic and quality-of-life considerations for its use as adjuvant therapy in women with breast cancer.

Authors:  H M Bryson; G L Plosker
Journal:  Pharmacoeconomics       Date:  1993-07       Impact factor: 4.981

2.  A survey of the management of breast cancer in England and Wales.

Authors:  S A Harries; R N Lawrence; R Scrivener; N R Fieldman; M W Kissin
Journal:  Ann R Coll Surg Engl       Date:  1996-05       Impact factor: 1.891

3.  Management of breast cancer.

Authors:  J Bell; A M Chouillet
Journal:  BMJ       Date:  1994-06-04

4.  Management of breast cancer in southeast England.

Authors:  A M Chouillet; C M Bell; J G Hiscox
Journal:  BMJ       Date:  1994-01-15

5.  Changes in incidence of and mortality from breast cancer in England and Wales since introduction of screening. United Kingdom Association of Cancer Registries.

Authors:  M Quinn; E Allen
Journal:  BMJ       Date:  1995-11-25

6.  Breast cancer care compared with clinical Guidelines: an observational study in France.

Authors:  Marie Lebeau; Simone Mathoulin-Pélissier; Carine Bellera; Christine Tunon-de-Lara; Alain Daban; Francis Lipinski; Dominique Jaubert; Pierre Ingrand; Virginie Migeot
Journal:  BMC Public Health       Date:  2011-01-20       Impact factor: 3.295

7.  The association between population-based treatment guidelines and adjuvant therapy for node-negative breast cancer. British Columbia/Ontario Working Group.

Authors:  C Sawka; I Olivotto; A Coldman; V Goel; E Holowaty; T G Hislop
Journal:  Br J Cancer       Date:  1997       Impact factor: 7.640

8.  Opinion: why the variation in breast cancer survival in Europe?

Authors:  M P Coleman
Journal:  Breast Cancer Res       Date:  1999-10-07       Impact factor: 6.466

9.  Variations in the management and survival of women under 50 years with breast cancer in the South East Thames region.

Authors:  M A Richards; C D Wolfe; K Tilling; J Barton; H M Bourne; W M Gregory
Journal:  Br J Cancer       Date:  1996-03       Impact factor: 7.640

10.  Why does specialist treatment of breast cancer improve survival? The role of surgical management.

Authors:  D Kingsmore; D Hole; C Gillis
Journal:  Br J Cancer       Date:  2004-05-17       Impact factor: 7.640

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