OBJECTIVE: To analyze the factors associated with survival and to describe the specific causes of death in a large cohort of individuals with Acquired Immune Deficiency Syndrome (AIDS) in the Highly Active Antiretroviral Therapy (HAART) era. METHODS: Subjects over 13 years old recorded in the AIDS registry of Barcelona and diagnosed between 1997-2005 were included. Survival analysis was performed. Causes of death were classified as being HIV-related or non-HIV-related. RESULTS: A total of 1,759 cases were analyzed, 640 (36.3%) of them died during the follow-up. The cumulative probability of survival at five years was of 64% (95% C.I. 62%-67%). The cause of death was non-HIV-related in 28.9% of the cases, among which the most frequent were cancers (20.8%) and liver diseases (18.8%). CONCLUSION: An increase in the proportion of non-HIV-related deaths has been observed compared to that in the pre-HAART era. The case management of HIV-infected people must be re-directed to influence the risk factors associated with these increasing causes of death.
OBJECTIVE: To analyze the factors associated with survival and to describe the specific causes of death in a large cohort of individuals with Acquired Immune Deficiency Syndrome (AIDS) in the Highly Active Antiretroviral Therapy (HAART) era. METHODS: Subjects over 13 years old recorded in the AIDS registry of Barcelona and diagnosed between 1997-2005 were included. Survival analysis was performed. Causes of death were classified as being HIV-related or non-HIV-related. RESULTS: A total of 1,759 cases were analyzed, 640 (36.3%) of them died during the follow-up. The cumulative probability of survival at five years was of 64% (95% C.I. 62%-67%). The cause of death was non-HIV-related in 28.9% of the cases, among which the most frequent were cancers (20.8%) and liver diseases (18.8%). CONCLUSION: An increase in the proportion of non-HIV-related deaths has been observed compared to that in the pre-HAART era. The case management of HIV-infectedpeople must be re-directed to influence the risk factors associated with these increasing causes of death.
Authors: Antonio G Pacheco; Suely H Tuboi; Silvia B May; Luiz F S Moreira; Luciana Ramadas; Estevão P Nunes; Mônica Merçon; José C Faulhaber; Lee H Harrison; Mauro Schechter Journal: J Acquir Immune Defic Syndr Date: 2009-08-15 Impact factor: 3.731
Authors: Katherine Krauskopf; Mark L Van Natta; Ronald P Danis; Sapna Gangaputra; Lori Ackatz; Adrienne Addessi; Alex D Federman; Andrea D Branch; Curtis L Meinert; Douglas A Jabs Journal: J Int Assoc Provid AIDS Care Date: 2013 Sep-Oct
Authors: Siavash Jafari; Keith Chan; Kewan Aboulhosn; Benita Yip; Viviane D Lima; Robert S Hogg; Julio Montaner; David M Moore Journal: AIDS Res Ther Date: 2011-09-05 Impact factor: 2.250
Authors: César Garriga; Patricia García de Olalla; Josep M Miró; Inma Ocaña; Hernando Knobel; Maria Jesús Barberá; Victoria Humet; Pere Domingo; Josep M Gatell; Esteve Ribera; Mercè Gurguí; Andrés Marco; Joan A Caylà Journal: PLoS One Date: 2015-12-30 Impact factor: 3.240
Authors: Shirish Barve; Rama Kapoor; Akshata Moghe; Julio A Ramirez; John W Eaton; Leila Gobejishvili; Swati Joshi-Barve; Craig J McClain Journal: Alcohol Res Health Date: 2010