OBJECTIVE: To examine prescription Food and Drug Administration (FDA) C, D and X drugs in general obstetric population. STUDY DESIGN: Historical cohort study. RESULT: A total of 18 575 women who gave a birth in Saskatchewan between January 1997 and December 2000 were included. Among them, 3604 (19.4%) received FDA C, D or X drugs at least once during pregnancy. The pregnancy exposure rates were 15.8, 5.2 and 3.9%, respectively, for category C, D and X drugs, and were 11.2, 7.3 and 8.2%, respectively, in the first, second and third trimesters. Salbutamol (albuterol), trimethoprim/sulfamethoxazole (co-trimoxazole), ibuprofen, naproxen and oral contraceptives were the most common C, D, X drugs used during pregnancy. CONCLUSION: About one in every five women uses FDA C, D and X drugs at least once during pregnancy, and the most common prescription drugs in pregnancy are antiasthmatic, antibiotics, nonsteroid anti-inflammation drugs, antianxiety or antidepressants and oral contraceptives.
OBJECTIVE: To examine prescription Food and Drug Administration (FDA) C, D and X drugs in general obstetric population. STUDY DESIGN: Historical cohort study. RESULT: A total of 18 575 women who gave a birth in Saskatchewan between January 1997 and December 2000 were included. Among them, 3604 (19.4%) received FDA C, D or X drugs at least once during pregnancy. The pregnancy exposure rates were 15.8, 5.2 and 3.9%, respectively, for category C, D and X drugs, and were 11.2, 7.3 and 8.2%, respectively, in the first, second and third trimesters. Salbutamol (albuterol), trimethoprim/sulfamethoxazole (co-trimoxazole), ibuprofen, naproxen and oral contraceptives were the most common C, D, X drugs used during pregnancy. CONCLUSION: About one in every five women uses FDA C, D and X drugs at least once during pregnancy, and the most common prescription drugs in pregnancy are antiasthmatic, antibiotics, nonsteroid anti-inflammation drugs, antianxiety or antidepressants and oral contraceptives.
Authors: Brian L Strom; Rita Schinnar; Joshua Jones; Warren B Bilker; Mark G Weiner; Sean Hennessy; Charles E Leonard; Peter F Cronholm; Eric Pifer Journal: J Am Med Inform Assoc Date: 2011-11-09 Impact factor: 4.497
Authors: Vinoj H Sewberath Misser; Arti Shankar; Ashna Hindori-Mohangoo; Jeffrey Wickliffe; Maureen Lichtveld; Dennis R A Mans Journal: Adv Pharmacoepidemiol Drug Saf Date: 2021-09-20
Authors: Millissia Ben Maamar; Laurianne Lesné; Kristin Hennig; Christèle Desdoits-Lethimonier; Karen R Kilcoyne; Isabelle Coiffec; Antoine D Rolland; Cécile Chevrier; David M Kristensen; Vincent Lavoué; Jean-Philippe Antignac; Bruno Le Bizec; Nathalie Dejucq-Rainsford; Rod T Mitchell; Séverine Mazaud-Guittot; Bernard Jégou Journal: Sci Rep Date: 2017-03-10 Impact factor: 4.379