Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Current topics in DNA double-strand break repair.

Literature DB >> 18285658

Current topics in DNA double-strand break repair.

Junya Kobayashi¹, Kuniyoshi Iwabuchi, Kiyoshi Miyagawa, Eiichiro Sonoda, Keiji Suzuki, Minoru Takata, Hiroshi Tauchi.

Abstract

DNA double strand break (DSB) is one of the most critical types of damage which is induced by ionizing radiation. In this review, we summarize current progress in investigations on the function of DSB repair-related proteins. We focused on recent findings in the analysis of the function of proteins such as 53BP1, histone H2AX, Mus81-Eme1, Fanc complex, and UBC13, which are found to be related to homologous recombination repair or to non-homologous end joining. In addition to the function of these proteins in DSB repair, the biological function of nuclear foci formation following DSB induction is discussed.

Entities: Gene

Mesh：

Substances：

Year: 2008 PMID： 18285658 DOI： 10.1269/jrr.07130

Source DB: PubMed Journal: J Radiat Res ISSN： 0449-3060 Impact factor: 2.724

Keyword Cloud
Cited

30 in total

1. Induction and repair of DNA double-strand breaks assessed by gamma-H2AX foci after irradiation with pulsed or continuous proton beams.

Authors: O Zlobinskaya; G Dollinger; D Michalski; V Hable; C Greubel; G Du; G Multhoff; B Röper; M Molls; T E Schmid
Journal: Radiat Environ Biophys Date: 2012-01-07 Impact factor: 1.925

2. DNA double-strand breaks as potential indicators for the biological effects of ionising radiation exposure from cardiac CT and conventional coronary angiography: a randomised, controlled study.

Authors: Dominik Geisel; Elke Zimmermann; Matthias Rief; Johannes Greupner; Michael Laule; Fabian Knebel; Bernd Hamm; Marc Dewey
Journal: Eur Radiol Date: 2012-04-17 Impact factor: 5.315

3. Fluorine-18-Labeled Thymidine Positron Emission Tomography (FLT-PET) as an Index of Cell Proliferation after Pharmacological Ascorbate-Based Therapy.

Authors: John A Cieslak; Zita A Sibenaller; Susan A Walsh; Laura L Boles Ponto; Juan Du; John J Sunderland; Joseph J Cullen
Journal: Radiat Res Date: 2015-12-31 Impact factor: 2.841

4. Genomic incompatibilities in the diploid and tetraploid offspring of the goldfish × common carp cross.

Authors: Shaojun Liu; Jing Luo; Jing Chai; Li Ren; Yi Zhou; Feng Huang; Xiaochuan Liu; Yubao Chen; Chun Zhang; Min Tao; Bin Lu; Wei Zhou; Guoliang Lin; Chao Mai; Shuo Yuan; Jun Wang; Tao Li; Qinbo Qin; Hao Feng; Kaikun Luo; Jun Xiao; Huan Zhong; Rurong Zhao; Wei Duan; Zhenyan Song; Yanqin Wang; Jing Wang; Li Zhong; Lu Wang; Zhaoli Ding; Zhenglin Du; Xuemei Lu; Yun Gao; Robert W Murphy; Yun Liu; Axel Meyer; Ya-Ping Zhang
Journal: Proc Natl Acad Sci U S A Date: 2016-01-14 Impact factor: 11.205

Current topics in DNA double-strand break repair.

1. Induction and repair of DNA double-strand breaks assessed by gamma-H2AX foci after irradiation with pulsed or continuous proton beams.

2. DNA double-strand breaks as potential indicators for the biological effects of ionising radiation exposure from cardiac CT and conventional coronary angiography: a randomised, controlled study.

3. Fluorine-18-Labeled Thymidine Positron Emission Tomography (FLT-PET) as an Index of Cell Proliferation after Pharmacological Ascorbate-Based Therapy.

4. Genomic incompatibilities in the diploid and tetraploid offspring of the goldfish × common carp cross.

5. ATF4 and IRE1α inhibit DNA repair protein DNA-dependent protein kinase 1 induced by heat shock.

6. Differentially expressed genes in response to gamma-irradiation during the vegetative stage in Arabidopsis thaliana.

7. TCRP1 promotes radioresistance of oral squamous cell carcinoma cells via Akt signal pathway.

8. Satellite cell senescence underlies myopathy in a mouse model of limb-girdle muscular dystrophy 2H.

9. Protein phosphatase 5 regulates the function of 53BP1 after neocarzinostatin-induced DNA damage.

10. microRNA-34a promotes DNA damage and mitotic catastrophe.