Literature DB >> 1828438

Molecular cloning of cDNA encoding adipogenesis inhibitory factor and identity with interleukin-11.

I Kawashima1, J Ohsumi, K Mita-Honjo, K Shimoda-Takano, H Ishikawa, S Sakakibara, K Miyadai, Y Takiguchi.   

Abstract

A cDNA encoding a novel adipogenesis inhibitory factor (AGIF) that inhibits the process of adipogenesis in mouse 3T3-L1 preadipocytes was cloned from a cDNA library of the human bone marrow-derived stromal cell line KM-102. The cloned cDNA contains an open reading frame coding for an AGIF precursor of 199 amino acids. Analysis of the sequence of this cDNA revealed identity of this factor with a recently reported novel cytokine, designated interleukin-11 (IL-11). AGIF/IL-11 may play an important role in stromal cell-associated hematopoeisis through its regulatory action on adipocyte differentiation in the bone marrow microenvironment.

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Year:  1991        PMID： 1828438     DOI： 10.1016/0014-5793(91)80587-s

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  23 in total

Review 1.  Adipogenesis.

Authors:  Kelesha Sarjeant; Jacqueline M Stephens
Journal:  Cold Spring Harb Perspect Biol       Date:  2012-09-01       Impact factor: 10.005

2.  Effects of interleukin-11 on the expression of human bone sialoprotein gene.

Authors:  Hiroyoshi Matsumura; Yohei Nakayama; Hideki Takai; Yorimasa Ogata
Journal:  J Bone Miner Metab       Date:  2014-03-15       Impact factor: 2.626

3.  Activation of the signal transducer gp130 by interleukin-11 and interleukin-6 is mediated by similar molecular interactions.

Authors:  H Dahmen; U Horsten; A Küster; Y Jacques; S Minvielle; I M Kerr; G Ciliberto; G Paonessa; P C Heinrich; G Müller-Newen
Journal:  Biochem J       Date:  1998-05-01       Impact factor: 3.857

Review 4.  Elucidating the Preadipocyte and Its Role in Adipocyte Formation: a Comprehensive Review.

Authors:  Christos N Sarantopoulos; Derek A Banyard; Mary E Ziegler; Beatrice Sun; Ashkaun Shaterian; Alan D Widgerow
Journal:  Stem Cell Rev Rep       Date:  2018-02       Impact factor: 5.739

Review 5.  The gp130 receptor cytokine family: regulators of adipocyte development and function.

Authors:  Ursula A White; Jacqueline M Stephens
Journal:  Curr Pharm Des       Date:  2011       Impact factor: 3.116

6.  Two differentially expressed interleukin-11 receptor genes in the mouse genome.

Authors:  P Bilinski; M A Hall; H Neuhaus; C Gissel; J K Heath; A Gossler
Journal:  Biochem J       Date:  1996-12-01       Impact factor: 3.857

7.  Interleukin-11 mRNA stabilization in phorbol ester-stimulated primate bone marrow stromal cells.

Authors:  L Yang; C N Steussy; D K Fuhrer; J Hamilton; Y C Yang
Journal:  Mol Cell Biol       Date:  1996-07       Impact factor: 4.272

8.  Functional characterization of W147A: a high-affinity interleukin-11 antagonist.

Authors:  Nicholas Underhill-Day; Lisa A McGovern; Natalia Karpovich; Helen J Mardon; Victoria A Barton; John K Heath
Journal:  Endocrinology       Date:  2003-08       Impact factor: 4.736

9.  Interleukin-11: a new cytokine critical for osteoclast development.

Authors:  G Girasole; G Passeri; R L Jilka; S C Manolagas
Journal:  J Clin Invest       Date:  1994-04       Impact factor: 14.808

10.  Interleukin-11 inhibits bone formation in vitro.

Authors:  F J Hughes; G L Howells
Journal:  Calcif Tissue Int       Date:  1993-11       Impact factor: 4.333
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