OBJECTIVE: To investigate the relationship between thyroid and kidney function. DESIGN AND METHODS: 13,383 results of serum creatinine and thyroid stimulating hormone (TSH) were retrieved from the database of our Laboratory. RESULTS: When compared with euthyroid subjects, those with TSH <0.2 mIU/L and >2.5 mIU/L had increased and decreased estimated glomerular filtration rate (e-GFR), respectively. TSH levels were an independent predictor of e-GFR. CONCLUSIONS: A mutual relationship was observed between kidney and thyroid status.
OBJECTIVE: To investigate the relationship between thyroid and kidney function. DESIGN AND METHODS: 13,383 results of serum creatinine and thyroid stimulating hormone (TSH) were retrieved from the database of our Laboratory. RESULTS: When compared with euthyroid subjects, those with TSH <0.2 mIU/L and >2.5 mIU/L had increased and decreased estimated glomerular filtration rate (e-GFR), respectively. TSH levels were an independent predictor of e-GFR. CONCLUSIONS: A mutual relationship was observed between kidney and thyroid status.