Literature DB >> 18280128

Regulation of secondary metabolite production in filamentous ascomycetes.

E Keats Shwab1, Nancy P Keller.   

Abstract

Fungi are renowned for their ability to produce bioactive small molecules otherwise known as secondary metabolites. These molecules have attracted much attention due to both detrimental (e.g. toxins) and beneficial (e.g. pharmaceuticals) effects on human endeavors. Once the topic only of chemical and biochemical studies, secondary metabolism research has reached a sophisticated level in the realm of genetic regulation. This review covers the latest insights into the processes regulating secondary metabolite production in filamentous fungi.

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Year:  2007        PMID： 18280128     DOI： 10.1016/j.mycres.2007.08.021

Source DB:  PubMed          Journal:  Mycol Res        ISSN： 0953-7562


  25 in total

1.  Characterization of an autoinducer of penicillin biosynthesis in Penicillium chrysogenum.

Authors:  Jorge Martín; Carlos García-Estrada; Angel Rumbero; Eliseo Recio; Silvia M Albillos; Ricardo V Ullán; Juan-Francisco Martín
Journal:  Appl Environ Microbiol       Date:  2011-07-01       Impact factor: 4.792

2.  Impact of velvet complex on transcriptome and penicillin G production in glucose-limited chemostat cultures of a β-lactam high-producing Penicillium chrysogenum strain.

Authors:  Tânia Veiga; Jeroen G Nijland; Arnold J M Driessen; Roel A L Bovenberg; Hesselein Touw; Marco A van den Berg; Jack T Pronk; Jean-Marc Daran
Journal:  OMICS       Date:  2012-03-22

3.  Transcription of genes in the biosynthetic pathway for fumonisin mycotoxins is epigenetically and differentially regulated in the fungal maize pathogen Fusarium verticillioides.

Authors:  I Visentin; V Montis; K Döll; C Alabouvette; G Tamietti; P Karlovsky; F Cardinale
Journal:  Eukaryot Cell       Date:  2011-11-23

4.  Two components of a velvet-like complex control hyphal morphogenesis, conidiophore development, and penicillin biosynthesis in Penicillium chrysogenum.

Authors:  Birgit Hoff; Jens Kamerewerd; Claudia Sigl; Rudolf Mitterbauer; Ivo Zadra; Hubert Kürnsteiner; Ulrich Kück
Journal:  Eukaryot Cell       Date:  2010-06-11

5.  Histone deacetylase inhibitors as a tool to up-regulate new fungal biosynthetic products: isolation of EGM-556, a cyclodepsipeptide, from Microascus sp.

Authors:  Hélène C Vervoort; Marija Drašković; Phillip Crews
Journal:  Org Lett       Date:  2010-12-21       Impact factor: 6.005

6.  Bacteria-induced static batch fungal fermentation of the diterpenoid cyathin A(3), a small-molecule inducer of nerve growth factor.

Authors:  Emma Dixon; Tatiana Schweibenz; Alison Hight; Brian Kang; Allyson Dailey; Sarah Kim; Meng-Yang Chen; Yura Kim; Sarah Neale; Ashley Groth; Trish Ike; Sarah Khan; Brandon Schweibenz; David Lieu; David Stone; Tania Orellana; Robin D Couch
Journal:  J Ind Microbiol Biotechnol       Date:  2010-08-17       Impact factor: 3.346

7.  NsdC and NsdD affect Aspergillus flavus morphogenesis and aflatoxin production.

Authors:  Jeffrey W Cary; Pamela Y Harris-Coward; Kenneth C Ehrlich; Brian M Mack; Shubha P Kale; Christy Larey; Ana M Calvo
Journal:  Eukaryot Cell       Date:  2012-07-13

8.  Relation of shear stress and KLa on bikaverin production by Fusarium oxysporum CCT7620 in a bioreactor.

Authors:  Marcela Colombo Dos Santos; Marcel O Cerri; Juliano Lemos Bicas
Journal:  Bioprocess Biosyst Eng       Date:  2022-01-23       Impact factor: 3.210

Review 9.  The chromatin code of fungal secondary metabolite gene clusters.

Authors:  Agnieszka Gacek; Joseph Strauss
Journal:  Appl Microbiol Biotechnol       Date:  2012-07-20       Impact factor: 4.813

10.  Activation of the dormant secondary metabolite production by introducing gentamicin-resistance in a marine-derived Penicillium purpurogenum G59.

Authors:  Yun-Jing Chai; Cheng-Bin Cui; Chang-Wei Li; Chang-Jing Wu; Cong-Kui Tian; Wei Hua
Journal:  Mar Drugs       Date:  2012-03-02       Impact factor: 6.085
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