Literature DB >> 18274892

A highly efficient construction of GM1 epitope tetrasaccharide and its conjugation with KLH.

Takeru Yoshikawa1, Yuki Kato, Nobuhiro Yuki, Tomio Yabe, Hideharu Ishida, Makoto Kiso.   

Abstract

GM1 epitope tetrasaccharide was synthesized by a condensation of sialyl-alpha(2-3)-gal acceptor and gal-beta(1-3)-GalN donor in a highly efficient manner. After introduction of mercaptohexanol to the tetrasaccharide, it was coupled to maleimide-activated KLH carrier protein to give the desired GM1 epitope-KLH conjugate.

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Year:  2008        PMID： 18274892     DOI： 10.1007/s10719-008-9111-2

Source DB:  PubMed          Journal:  Glycoconj J        ISSN： 0282-0080            Impact factor:   2.916


  13 in total

1.  Binding properties and esterase activity of monoclonal antibodies elicited against sucrose 6-heptylphosphonate.

Authors:  M C Scherrmann; A Boutboul; B Estramareix; A S Hoffmann; A Lubineau
Journal:  Carbohydr Res       Date:  2001-09-07       Impact factor: 2.104

2.  Comparison of two methods of preparing enzyme-antibody conjugates: application of these conjugates for enzyme immunoassay.

Authors:  M J O'Sullivan; E Gnemmi; D Morris; G Chieregatti; A D Simmonds; M Simmons; J W Bridges; V Marks
Journal:  Anal Biochem       Date:  1979-11-15       Impact factor: 3.365

3.  A comparison between the sulfhydryl reductants tris(2-carboxyethyl)phosphine and dithiothreitol for use in protein biochemistry.

Authors:  E B Getz; M Xiao; T Chakrabarty; R Cooke; P R Selvin
Journal:  Anal Biochem       Date:  1999-08-15       Impact factor: 3.365

4.  Synthesis and enzymatic susceptibility of a series of novel GM2 analogs.

Authors:  Tomoaki Fuse; Hiromune Ando; Akihiro Imamura; Naoki Sawada; Hideharu Ishida; Makoto Kiso; Takayuki Ando; Su-Chen Li; Yu-Teh Li
Journal:  Glycoconj J       Date:  2006-07       Impact factor: 2.916

Review 5.  Gangliosides and glycosphingolipids of peripheral nervous system myelins--a minireview.

Authors:  K Ogawa-Goto; T Abe
Journal:  Neurochem Res       Date:  1998-03       Impact factor: 3.996

6.  Animal model of axonal Guillain-Barré syndrome induced by sensitization with GM1 ganglioside.

Authors:  N Yuki; M Yamada; M Koga; M Odaka; K Susuki; Y Tagawa; S Ueda; T Kasama; A Ohnishi; S Hayashi; H Takahashi; M Kamijo; K Hirata
Journal:  Ann Neurol       Date:  2001-06       Impact factor: 10.422

7.  Di-tert-butylsilylene-directed alpha-selective synthesis of 4-methylumbelliferyl T-antigen.

Authors:  Akihiro Imamura; Hiromune Ando; Hideharu Ishida; Makoto Kiso
Journal:  Org Lett       Date:  2005-09-29       Impact factor: 6.005

Review 8.  Infectious origins of, and molecular mimicry in, Guillain-Barré and Fisher syndromes.

Authors:  N Yuki
Journal:  Lancet Infect Dis       Date:  2001-08       Impact factor: 25.071

9.  Carbohydrate mimicry between human ganglioside GM1 and Campylobacter jejuni lipooligosaccharide causes Guillain-Barre syndrome.

Authors:  Nobuhiro Yuki; Keiichiro Susuki; Michiaki Koga; Yukihiro Nishimoto; Masaaki Odaka; Koichi Hirata; Kyoji Taguchi; Tadashi Miyatake; Koichi Furukawa; Tetsuji Kobata; Mitsunori Yamada
Journal:  Proc Natl Acad Sci U S A       Date:  2004-07-26       Impact factor: 11.205

10.  Immunoglobulin improves a model of acute motor axonal neuropathy by preventing axonal degeneration.

Authors:  Y Nishimoto; M Koga; M Kamijo; K Hirata; N Yuki
Journal:  Neurology       Date:  2004-06-08       Impact factor: 9.910
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  2 in total

1.  Synthesis of Neoglycoconjugates Containing 4-Amino-4-deoxy-l-arabinose Epitopes Corresponding to the Inner Core of Burkholderia and Proteus Lipopolysaccharides.

Authors:  Markus Blaukopf; Bernhard Müller; Andreas Hofinger; Paul Kosma
Journal:  European J Org Chem       Date:  2011-11-16

2.  Design and synthesis of versatile ganglioside probes for carbohydrate microarrays.

Authors:  Akihiro Imamura; Takeru Yoshikawa; Tatsuya Komori; Masatoshi Ando; Hiromune Ando; Masahiro Wakao; Yasuo Suda; Hideharu Ishida; Makoto Kiso
Journal:  Glycoconj J       Date:  2008-01-16       Impact factor: 3.009
  2 in total

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