Meinolf Karthaus1. 1. Dept. Hämatologie und Onkologie, Klinikum Neuperlach, Oskar-Maria-Graf Ring 51, 81737, Munich, Germany. m.karthaus@kh-neuperlach.de
Abstract
BACKGROUND: The use of indwelling central venous catheters (CVCs) for chemotherapy delivery is common practice in cancer patients. Central venous lines facilitate ease of blood drawing along with administration of blood products and various other therapies. Significant risks, however, include infection and catheter-related thrombosis. Several attempts have been investigated to reduce CVC-associated thrombosis, in particular anticoagulation strategies. Given the lack of clear efficacy, there is at present no recommendation for the use of prophylactic anti-coagulation in patients with solid malignancy and an indwelling CVC. MATERIALS AND METHODS: This paper reviews recent given recommendations based on controlled trials.
BACKGROUND: The use of indwelling central venous catheters (CVCs) for chemotherapy delivery is common practice in cancerpatients. Central venous lines facilitate ease of blood drawing along with administration of blood products and various other therapies. Significant risks, however, include infection and catheter-related thrombosis. Several attempts have been investigated to reduce CVC-associated thrombosis, in particular anticoagulation strategies. Given the lack of clear efficacy, there is at present no recommendation for the use of prophylactic anti-coagulation in patients with solid malignancy and an indwelling CVC. MATERIALS AND METHODS: This paper reviews recent given recommendations based on controlled trials.