Literature DB >> 18272741

Changes in traditional risk factors no longer explain time trends in cardiovascular mortality and its socioeconomic differences.

K Harald1, S Koskinen, P Jousilahti, J Torppa, E Vartiainen, V Salomaa.   

Abstract

AIM: To investigate to what extent the changes in traditional risk factors (total cholesterol, smoking, hypertension) explain the changes in socioeconomic (defined by occupational class and household income) differences in cardiovascular mortality in Finland during the past 20 years.
DESIGN: Study population comprised 14,642 men and women aged 35-64 years who were selected from population-based FINRISK surveys in 1987, 1992, 1997 or 2002 in three areas of Finland. The 1982 and 1987 FINRISK cohorts were used to determine a model for the probability of cardiovascular death based on risk factor values at the baseline for each socioeconomic group. These predicted changes in cardiovascular mortality were then contrasted with observed mortality rates in different socioeconomic groups to determine the contribution of the changes in risk factors to changes in actual mortality.
RESULTS: We found that among men during 1987-97, when risk factor levels were improving in all socioeconomic groups, the model explained 29-44% of the observed mortality decline. The risk factors explained a larger part of the decline among lower socioeconomic groups. During the period 1997-2002 the risk factor levels stopped improving in all socioeconomic groups but observed mortality rates kept declining. The predicted mortality rates were 16-34% of the observed rates during the period 1987-2002.
CONCLUSIONS: Changes in traditional risk factors no longer provide a good explanation of the changes in cardiovascular mortality and its socioeconomic differences. However, risk factors did explain the cardiovascular mortality decline among lower socioeconomic groups.

Entities:  

Mesh:

Substances:

Year:  2008        PMID: 18272741     DOI: 10.1136/jech.2007.060707

Source DB:  PubMed          Journal:  J Epidemiol Community Health        ISSN: 0143-005X            Impact factor:   3.710


  12 in total

1.  Combined hyperlipidemia in patients with lysinuric protein intolerance.

Authors:  Laura M Tanner; Harri Niinikoski; Kirsti Näntö-Salonen; Olli Simell
Journal:  J Inherit Metab Dis       Date:  2010-02-23       Impact factor: 4.982

2.  Do biological measures mediate the relationship between education and health: A comparative study.

Authors:  Noreen Goldman; Cassio M Turra; Luis Rosero-Bixby; David Weir; Eileen Crimmins
Journal:  Soc Sci Med       Date:  2010-11-23       Impact factor: 4.634

3.  To what extent do biomarkers account for the large social disparities in health in Moscow?

Authors:  Dana A Glei; Noreen Goldman; Vladimir M Shkolnikov; Dmitri Jdanov; Svetlana Shalnova; Maria Shkolnikova; Maxine Weinstein
Journal:  Soc Sci Med       Date:  2012-11-27       Impact factor: 4.634

4.  Trends in risk factors for cardiovascular disease in Canada: temporal, socio-demographic and geographic factors.

Authors:  Douglas S Lee; Maria Chiu; Douglas G Manuel; Karen Tu; Xuesong Wang; Peter C Austin; Michelle Y Mattern; Tezeta F Mitiku; Lawrence W Svenson; Wayne Putnam; William M Flanagan; Jack V Tu
Journal:  CMAJ       Date:  2009-07-20       Impact factor: 8.262

5.  Persistent pathogens linking socioeconomic position and cardiovascular disease in the US.

Authors:  Amanda M Simanek; Jennifer Beam Dowd; Allison E Aiello
Journal:  Int J Epidemiol       Date:  2008-12-24       Impact factor: 7.196

6.  A prospective study of bone lead concentration and death from all causes, cardiovascular diseases, and cancer in the Department of Veterans Affairs Normative Aging Study.

Authors:  Marc G Weisskopf; Nitin Jain; Huiling Nie; David Sparrow; Pantel Vokonas; Joel Schwartz; Howard Hu
Journal:  Circulation       Date:  2009-09-08       Impact factor: 29.690

7.  Trends in adult cardiovascular disease risk factors and their socio-economic patterning in the Scottish population 1995-2008: cross-sectional surveys.

Authors:  Joel W Hotchkiss; Carolyn Davies; Linsay Gray; Catherine Bromley; Simon Capewell; Alastair H Leyland
Journal:  BMJ Open       Date:  2011-08-09       Impact factor: 2.692

8.  Coronary heart disease mortality among young adults in Scotland in relation to social inequalities: time trend study.

Authors:  Martin O'Flaherty; Jennifer Bishop; Adam Redpath; Terry McLaughlin; David Murphy; James Chalmers; Simon Capewell
Journal:  BMJ       Date:  2009-07-14

9.  Analysing recent socioeconomic trends in coronary heart disease mortality in England, 2000-2007: a population modelling study.

Authors:  Madhavi Bajekal; Shaun Scholes; Hande Love; Nathaniel Hawkins; Martin O'Flaherty; Rosalind Raine; Simon Capewell
Journal:  PLoS Med       Date:  2012-06-12       Impact factor: 11.069

10.  Role of secretory phospholipase A₂ in women with metabolic syndrome.

Authors:  D Pop; A Sitar-Taut; G Bodisz; D Zdrenghea; M Cebanu; L Stanca
Journal:  Indian J Med Res       Date:  2013-12       Impact factor: 2.375

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.