Literature DB >> 18271420

[Can a standard treatment be proposed for penile cancer?].

Jean-Nicolas Cornu1, Eva Comperat, Raphaële Renard-Penna, Vincent Misrai, Marc-Olivier Bitker, Alain Haertig, Emmanuel Chartier-Kastler, François Richard, Morgan Roupret.   

Abstract

OBJECTIVE: Malignant tumours of the penis are rare and their management is complex. The objective of this study was to review the management and report the results based on a personal series.
MATERIALS AND METHODS: Cases of penile cancer treated in our department between 2000 and 2006 were retrospectively reviewed. The following data were recorded: mode of presentation, staging, site, pathology, TNM stage, treatment, course and survival.
RESULTS: Seven cases of squamous cell carcinoma of the penis were diagnosed. The mean age of the patients was 58.8 years (range: 41-74), Two precancerous lesions (Bowen's disease) and one case of Human Papilloma Virus (HPV) infection were observed. Five patients received multimodal conservative treatment and 2 patients were treated by total amputation of the penis. Four patients have died. The mean survival was 19.3 months and the 5-year specific survival was 42.8%.
CONCLUSION: Cancers of the penis are aggressive tumours with a poor prognosis. Treatment decisions, which are poorly defined in these cases of rare cancers, should be based on multidisciplinary consultations.

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Year:  2007        PMID: 18271420     DOI: 10.1016/s1166-7087(07)78575-5

Source DB:  PubMed          Journal:  Prog Urol        ISSN: 1166-7087            Impact factor:   0.915


  1 in total

1.  New cancer cases in France in 2015 attributable to infectious agents: a systematic review and meta-analysis.

Authors:  Kevin David Shield; Claire Marant Micallef; Catherine de Martel; Isabelle Heard; Francis Megraud; Martyn Plummer; Jérôme Vignat; Freddie Bray; Isabelle Soerjomataram
Journal:  Eur J Epidemiol       Date:  2017-12-06       Impact factor: 8.082

  1 in total

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