Literature DB >> 18268856

Administration of 75 mg of aspirin daily for 28 days is sufficient prophylaxis against renal transplant vein thrombosis.

M J Stechman1, N Charlwood, D W R Gray, A Handa.   

Abstract

INTRODUCTION: Early postoperative renal transplant vein thrombosis results in graft loss. We evaluate the effect of administering aspirin 75 mg daily for 28 days following transplantation.
METHODS: Prospectively collected data on the outcome of all transplants undertaken in our unit in the five-year period from January 1997 to January 2002 were reviewed, and in cases of graft failure before three months the cause was defined.
RESULTS: In the study period, a total of 401 transplants were undertaken (311 cadaveric and 90 living related). There was one case of renal transplant vein thrombosis (0.25%). This represents a significant reduction on the unit's historical incidence of 5.8%, P < 0.001.
CONCLUSION: Aspirin 75 mg daily is adequate to virtually abolish renal transplant vein thrombosis and has a role in thromboprophylaxis in other situations where heparin is contraindicated.

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Year:  2007        PMID: 18268856     DOI: 10.1258/026835507780346187

Source DB:  PubMed          Journal:  Phlebology        ISSN: 0268-3555            Impact factor:   1.740


  8 in total

Review 1.  Small cells, big effects: the role of platelets in transplant vasculopathy.

Authors:  Kristina L Modjeski; Craig N Morrell
Journal:  J Thromb Thrombolysis       Date:  2014-01       Impact factor: 2.300

2.  Aspirin significantly decreases the nonopsonic phagocytosis and immunogenicity of macrophages in mice.

Authors:  Aqeel Javeed; Yuzhu Hou; Kaizhong Duan; Baojun Zhang; Hong Shen; Yuhong Cao; Yong Zhao
Journal:  Inflamm Res       Date:  2010-12-01       Impact factor: 4.575

Review 3.  Acute graft thrombosis in patients who underwent renal transplant and received anticoagulant or antiplatelet agents. A systematic review and meta-analysis.

Authors:  Rodrigo Guerra; Paulo Roberto Kawano; Marcelo Petean Amaro; Hamilto Akihissa Yamamoto; Fernando Ferreira Gomes Filho; João Luiz Amaro; Regina Paolucci El Dib; Herney Andres Garcia-Perdomo; Leonardo Oliveira Reis
Journal:  Am J Clin Exp Urol       Date:  2022-06-15

Review 4.  Prophylaxis of Pulmonary Embolism in Kidney Transplant Recipients.

Authors:  Federico Cicora; Jorgelina Petroni; Javier Roberti
Journal:  Curr Urol Rep       Date:  2018-02-23       Impact factor: 3.092

5.  Identification of risk factors for vascular thrombosis may reduce early renal graft loss: a review of recent literature.

Authors:  Anna Krarup Keller; Troels Munch Jorgensen; Bente Jespersen
Journal:  J Transplant       Date:  2012-05-31

6.  Post transplant renal vein thrombosis, with successful thrombectomy and review of the literature.

Authors:  Mark Lerman; Matthew Mulloy; Christie Gooden; Salman Khan; Ali Khalil; Lincoln Patel; Xin J Zhou
Journal:  Int J Surg Case Rep       Date:  2019-07-31

7.  Unexpected success in early post-transplantation renal vein thrombosis: A case report and literature review.

Authors:  Joana Eugénio Santos; Ana Gaspar; Sara Querido; Cristina Jorge; André Weigert; Henrique Mesquita Gabriel; António Martinho; Domingos Machado
Journal:  Clin Nephrol Case Stud       Date:  2021-02-19

Review 8.  The effect of aspirin on kidney allograft outcomes; a short review to current studies.

Authors:  Wisit Cheungpasitporn; Charat Thongprayoon; Donald G Mitema; Michael A Mao; Ankit Sakhuja; Wonngarm Kittanamongkolchai; Maria L Gonzalez-Suarez; Stephen B Erickson
Journal:  J Nephropathol       Date:  2017-01-30
  8 in total

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