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Literature DB >> 18264734

EJCP and clinical toxicology: the first 40 years.

Abstract

INTRODUCTION: The European Journal of Clinical Pharmacology is now 40 years old and its history and development parallel developments in the related discipline of clinical (medical) toxicology. The journal has published many papers over its history that have informed its readers of scientific advances that link clinical pharmacology and clinical toxicology. DISCUSSION: This review will provide an overview of the developments in treatment of poisoning and how effects of poisoning may provide information for drug regulation and suggests ways in which developments in pharmacogenetics and metabolomics may stimulate future research in this area.

Entities: Chemical Disease

Mesh：

Substances：
Antidotes

Year: 2007 PMID： 18264734 DOI： 10.1007/s00228-007-0405-2

Source DB: PubMed Journal: Eur J Clin Pharmacol ISSN： 0031-6970 Impact factor: 2.953

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References

21 in total

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Authors: T Ahola; V Fellman; R Laaksonen; J Laitila; R Lapatto; P J Neuvonen; K O Raivio
Journal: Eur J Clin Pharmacol Date: 1999-11 Impact factor: 2.953

2. Co-proxamol overdose is associated with a 10-fold excess mortality compared with other paracetamol combination analgesics.

Authors: R Afshari; A M Good; S R J Maxwell; D N Bateman
Journal: Br J Clin Pharmacol Date: 2005-10 Impact factor: 4.335

Review 3. Position statement: ipecac syrup. American Academy of Clinical Toxicology; European Association of Poisons Centres and Clinical Toxicologists.

Authors: E P Krenzelok; M McGuigan; P Lheur
Journal: J Toxicol Clin Toxicol Date: 1997

Review 4. Position statement: gastric lavage. American Academy of Clinical Toxicology; European Association of Poisons Centres and Clinical Toxicologists.

Authors: J A Vale
Journal: J Toxicol Clin Toxicol Date: 1997

5. Kinetics of the Fab fragments of digoxin antibodies and of bound digoxin in patients with severe digoxin intoxication.

Authors: W Schaumann; B Kaufmann; P Neubert; A Smolarz
Journal: Eur J Clin Pharmacol Date: 1986 Impact factor: 2.953

EJCP and clinical toxicology: the first 40 years.

1. Pharmacokinetics of intravenous N-acetylcysteine in pre-term new-born infants.

2. Co-proxamol overdose is associated with a 10-fold excess mortality compared with other paracetamol combination analgesics.

Review 3. Position statement: ipecac syrup. American Academy of Clinical Toxicology; European Association of Poisons Centres and Clinical Toxicologists.

Review 4. Position statement: gastric lavage. American Academy of Clinical Toxicology; European Association of Poisons Centres and Clinical Toxicologists.

5. Kinetics of the Fab fragments of digoxin antibodies and of bound digoxin in patients with severe digoxin intoxication.

6. Antidepressants in suicide: differences in fatality and drug utilisation.

7. The disposition and kinetics of intravenous N-acetylcysteine in patients with paracetamol overdosage.

8. Fatal intoxication cases: cytochrome P450 2D6 and 2C19 genotype distributions.

9. Electrocardiogram and cardiovascular changes in thioridazine and chlorpromazine poisoning.

10. Comparison of activated charcoal and ipecac syrup in prevention of drug absorption.