Literature DB >> 18257536

Ciliatamides A-C, bioactive lipopeptides from the deep-sea sponge Aaptos ciliata.

Yoichi Nakao1, Shizuka Kawatsu, Chikane Okamoto, Masaaki Okamoto, Yoshitsugu Matsumoto, Shigeki Matsunaga, Rob W M van Soest, Nobuhiro Fusetani.   

Abstract

Three lipopeptides, ciliatamides A-C ( 1- 3), were isolated from the deep-sea sponge Aaptos ciliata, and their structures were elucidated on the basis of spectroscopic and chemical methods. Ciliatamides A ( 1) and B ( 2) were found to be antileishmanial, while 2 also exhibited marginal cytotoxicity to HeLa cells.

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Year:  2008        PMID: 18257536     DOI: 10.1021/np8000317

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


  4 in total

Review 1.  The structural diversity and promise of antiparasitic marine invertebrate-derived small molecules.

Authors:  Katharine R Watts; Karen Tenney; Phillip Crews
Journal:  Curr Opin Biotechnol       Date:  2010-10-16       Impact factor: 9.740

2.  Total synthesis of Ciliatamides A-C: stereochemical revision and the natural product-guided synthesis of unnatural analogs.

Authors:  Jana A Lewis; R Nathan Daniels; Craig W Lindsley
Journal:  Org Lett       Date:  2008-09-13       Impact factor: 6.005

Review 3.  Bioactive compounds from marine invertebrates as potent anticancer drugs: the possible pharmacophores modulating cell death pathways.

Authors:  Srimanta Patra; Prakash Priyadarshi Praharaj; Debasna Pritimanjari Panigrahi; Biswajit Panda; Chandra Sekhar Bhol; Kewal Kumar Mahapatra; Soumya Ranjan Mishra; Bishnu Prasad Behera; Mrutyunjay Jena; Gautam Sethi; Shankargouda Patil; Samir Kumar Patra; Sujit Kumar Bhutia
Journal:  Mol Biol Rep       Date:  2020-08-14       Impact factor: 2.316

Review 4.  The Pharmacological Potential of Non-ribosomal Peptides from Marine Sponge and Tunicates.

Authors:  Shivankar Agrawal; Alok Adholeya; Sunil K Deshmukh
Journal:  Front Pharmacol       Date:  2016-10-25       Impact factor: 5.810

  4 in total

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