| Literature DB >> 1825668 |
S Otake1, Y Nishihara, M Makimura, H Hatta, M Kim, T Yamamoto, M Hirasawa.
Abstract
Hen-egg-yolk antibody (IgY) was prepared against Streptococcus mutans MT8148 serotype c that was cultivated in medium containing sucrose, and it was used in passive caries-immunity studies. Specific pathogen-free rats infected with S. mutans MT8148 (c) and fed with a cariogenic diet containing more than 2% immune yolk powder developed significantly lower caries scores than did the ones infected with the same strain and fed with a diet containing only control yolk powder obtained from non-immunized hens. Similar results were obtained in an experiment with rats infected with S. mutans JC-2 (c) strain. Rats provided a diet supplemented with 0.5% immune water-soluble protein fraction containing S. mutans-specific IgY and challenged with S. mutans MT8148 exhibited significantly fewer caries lesions, compared with control rats on the normal diet.Entities:
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Year: 1991 PMID： 1825668 DOI： 10.1177/00220345910700030101
Source DB: PubMed Journal: J Dent Res ISSN： 0022-0345 Impact factor: 6.116