OBJECTIVE: This study aims to evaluate the eff ect of soybean milk containing a combination of anti-Streptococcus mutans IgY and chitosan to the colonization of S. mutans in the saliva and to the IgY persistency in the saliva. MATERIALS AND METHODS: Experimental malnourished Sprague-Dawley rats were fed with soybean milk that is enriched with anti-S. mutans IgY and chitosan. After 15 days of feeding, we evaluated the S. mutans in dental biofilm, in addition to the persistency level of anti-S. mutans IgY. RESULTS: The rats that received soybean milk supplemented with anti-S. mutans IgY had the lowest number of S. mutans colonies (p < 0.05). Anti-S. mutans IgY was detected in saliva after 15 days of feeding. CONCLUSIONS: Soybean milk supplemented with anti-S. mutans IgY and chitosan could signifi cantly reduce S. mutans biofilm, and the supplemented anti-S. mutans IgY persisted in these rats' saliva following the feeding period.
OBJECTIVE: This study aims to evaluate the eff ect of soybean milk containing a combination of anti-Streptococcus mutans IgY and chitosan to the colonization of S. mutans in the saliva and to the IgY persistency in the saliva. MATERIALS AND METHODS: Experimental malnourished Sprague-Dawley rats were fed with soybean milk that is enriched with anti-S. mutans IgY and chitosan. After 15 days of feeding, we evaluated the S. mutans in dental biofilm, in addition to the persistency level of anti-S. mutans IgY. RESULTS: The rats that received soybean milk supplemented with anti-S. mutans IgY had the lowest number of S. mutans colonies (p < 0.05). Anti-S. mutans IgY was detected in saliva after 15 days of feeding. CONCLUSIONS:Soybean milk supplemented with anti-S. mutans IgY and chitosan could signifi cantly reduce S. mutans biofilm, and the supplemented anti-S. mutans IgY persisted in these rats' saliva following the feeding period.
Entities:
Keywords:
IgY; S. mutans; biofilm; chitosan; soy milk
Authors: S G Dashper; B N Saion; M A Stacey; D J Manton; N J Cochrane; D P Stanton; Y Yuan; E C Reynolds Journal: J Dent Date: 2012-05-17 Impact factor: 4.379