Literature DB >> 18245598

Instability-associated changes in contact stress and contact stress rates near a step-off incongruity.

Todd O McKinley1, Yuki Tochigi, M James Rudert, Thomas D Brown.   

Abstract

BACKGROUND: Intra-articular fractures can result in articular surface incongruity and joint instability, both of which can lead to posttraumatic osteoarthritis. The purpose of this study was to quantify changes in contact stresses and contact stress rates in incongruous human cadaveric ankles that were either stable or unstable. It was hypothesized that joint instability, superimposed on articular incongruity, would cause significant increases in contact stresses and contact stress rates.
METHODS: Intact human cadaveric ankles were subjected to quasi-physiologic stance-phase motion and loading, and instantaneous contact stresses were captured at 132 Hz. The anterior one-third of the distal part of the tibia was displaced proximally by 2.0 mm, and testing was repeated. Anterior/posterior forces were modulated during loading to cause incongruous ankles to either remain stable or become unstable during loading. Transient contact stresses and contact stress rates were measured for seven ankles under intact, stable-incongruous, and unstable-incongruous conditions. Peak and 95th percentile values of contact stress and contact stress rates for all three conditions were compared to determine the pathomechanical effects of incongruity and instability.
RESULTS: The addition of instability caused 95th percentile and peak contact stresses to increase approximately between 20% and 25% in the unstable-incongruous specimens compared with the stable-incongruous specimens. In contrast, the addition of instability increased the magnitude of peak positive and peak negative contact stress rates by 115% and 170% in the unstable-incongruous specimens compared with the stable-incongruous specimens. Similarly, the 95th percentile contact stress rates increased 112% in the unstable-incongruous specimens compared with the stable-incongruous specimens.
CONCLUSIONS: In human cadaveric ankles, instability superimposed on an existing articular surface incongruity causes disproportionate increases in contact stress rates compared with the increases in contact stresses.

Entities:  

Mesh:

Year:  2008        PMID: 18245598      PMCID: PMC2587164          DOI: 10.2106/JBJS.G.00127

Source DB:  PubMed          Journal:  J Bone Joint Surg Am        ISSN: 0021-9355            Impact factor:   5.284


  31 in total

1.  Induction of chondrocyte apoptosis following impact load.

Authors:  Joseph Borrelli; Kevin Tinsley; William M Ricci; Meghan Burns; Irene E Karl; Richard Hotchkiss
Journal:  J Orthop Trauma       Date:  2003-10       Impact factor: 2.512

2.  Compositional and metabolic changes in damaged cartilage are peak-stress, stress-rate, and loading-duration dependent.

Authors:  C T Chen; N Burton-Wurster; G Lust; R A Bank; J M Tekoppele
Journal:  J Orthop Res       Date:  1999-11       Impact factor: 3.494

3.  Contact stress transients during functional loading of ankle stepoff incongruities.

Authors:  Todd O McKinley; M James Rudert; Daniel C Koos; Douglas R Pedersen; Thomas E Baer; Yuki Tochigi; Thomas D Brown
Journal:  J Biomech       Date:  2005-05-31       Impact factor: 2.712

4.  Incongruity-dependent changes of contact stress rates in human cadaveric ankles.

Authors:  Todd O McKinley; M James Rudert; Yuki Tochigi; Douglas R Pedersen; Daniel C Koos; Thomas E Baer; Thomas D Brown
Journal:  J Orthop Trauma       Date:  2006 Nov-Dec       Impact factor: 2.512

5.  Quantitation and localization of cartilage degeneration following the induction of osteoarthritis in the rabbit knee.

Authors:  D G Chang; E P Iverson; R M Schinagl; M Sonoda; D Amiel; R D Coutts; R L Sah
Journal:  Osteoarthritis Cartilage       Date:  1997-09       Impact factor: 6.576

6.  Effect of impact on chondrocyte viability during insertion of human osteochondral grafts.

Authors:  Boris H Borazjani; Albert C Chen; Won C Bae; Shantanu Patil; Robert L Sah; Gary S Firestein; William D Bugbee
Journal:  J Bone Joint Surg Am       Date:  2006-09       Impact factor: 5.284

Review 7.  The deformation behavior and viscoelastic properties of chondrocytes in articular cartilage.

Authors:  F Guilak
Journal:  Biorheology       Date:  2000       Impact factor: 1.875

8.  Analysis of acute mechanical insult in an animal model of post-traumatic osteoarthrosis.

Authors:  W N Newberry; J J Garcia; C D Mackenzie; C E Decamp; R C Haut
Journal:  J Biomech Eng       Date:  1998-12       Impact factor: 2.097

9.  Cartilage injury by ramp compression near the gel diffusion rate.

Authors:  Véronique Morel; Thomas M Quinn
Journal:  J Orthop Res       Date:  2004-01       Impact factor: 3.494

10.  Instability of the elbow treated with semiconstrained total elbow arthroplasty.

Authors:  M L Ramsey; R A Adams; B F Morrey
Journal:  J Bone Joint Surg Am       Date:  1999-01       Impact factor: 5.284

View more
  13 in total

1.  Injurious Loading of Articular Cartilage Compromises Chondrocyte Respiratory Function.

Authors:  Mitchell C Coleman; Prem S Ramakrishnan; Marc J Brouillette; James A Martin
Journal:  Arthritis Rheumatol       Date:  2016-03       Impact factor: 10.995

2.  An instrumented pendulum system for measuring energy absorption during fracture insult to large animal joints in vivo.

Authors:  B W Diestelmeier; M J Rudert; Y Tochigi; T E Baer; D C Fredericks; T D Brown
Journal:  J Biomech Eng       Date:  2014-06       Impact factor: 2.097

3.  The role of mechanical forces in the initiation and progression of osteoarthritis.

Authors:  Joseph A Buckwalter
Journal:  HSS J       Date:  2012-02-14

4.  In Vivo Syndesmotic Overcompression After Fixation of Ankle Fractures With a Syndesmotic Injury.

Authors:  Steven M Cherney; Jacob A Haynes; Amanda G Spraggs-Hughes; Christopher M McAndrew; William M Ricci; Michael J Gardner
Journal:  J Orthop Trauma       Date:  2015-09       Impact factor: 2.512

5.  A new sensor for measurement of dynamic contact stress in the hip.

Authors:  M J Rudert; B J Ellis; C R Henak; N J Stroud; D R Pederson; J A Weiss; T D Brown
Journal:  J Biomech Eng       Date:  2014-03       Impact factor: 2.097

6.  Do Spatiotemporal Gait Parameters Improve After Pilon Fracture in Patients Who Use the Intrepid Dynamic Exoskeletal Orthosis?

Authors:  Michael Quacinella; Ethan Bernstein; Brittney Mazzone; Marilynn Wyatt; Kevin M Kuhn
Journal:  Clin Orthop Relat Res       Date:  2019-04       Impact factor: 4.176

7.  Organ-level histological and biomechanical responses from localized osteoarticular injury in the rabbit knee.

Authors:  Tanawat Vaseenon; Yuki Tochigi; Anneliese D Heiner; Jessica E Goetz; Thomas E Baer; Douglas C Fredericks; James A Martin; M James Rudert; Stephen L Hillis; Thomas D Brown; Todd O McKinley
Journal:  J Orthop Res       Date:  2010-09-30       Impact factor: 3.494

Review 8.  Peculiarities in Ankle Cartilage.

Authors:  Matthew J Kraeutler; Tanyaporn Kaenkumchorn; Cecilia Pascual-Garrido; Markus A Wimmer; Susanna Chubinskaya
Journal:  Cartilage       Date:  2016-04-11       Impact factor: 4.634

9.  Complementary models reveal cellular responses to contact stresses that contribute to post-traumatic osteoarthritis.

Authors:  James A Martin; Donald D Anderson; Jessica E Goetz; Douglas Fredericks; Douglas R Pedersen; Bruce P Ayati; J Lawrence Marsh; Joseph A Buckwalter
Journal:  J Orthop Res       Date:  2016-08-26       Impact factor: 3.494

10.  Treatment of ankle osteoarthritis: arthrodesis versus total ankle replacement.

Authors:  N Espinosa; G Klammer
Journal:  Eur J Trauma Emerg Surg       Date:  2010-11-13       Impact factor: 3.693

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.