Literature DB >> 18245412

Burden and economic cost of group A streptococcal pharyngitis.

Elizabeth Pfoh1, Michael R Wessels, Donald Goldmann, Grace M Lee.   

Abstract

OBJECTIVE: Our aim was to describe the morbidity, medical costs, and nonmedical costs associated with group A streptococcal pharyngitis in school-aged children.
METHODS: Our study population included parents of children diagnosed as having group A streptococcal pharyngitis at 2 pediatric practice sites in the Boston, Massachusetts, metropolitan area. Telephone interviews were conducted with parents of eligible children, who were asked questions about health care utilization, medications, and time missed from work or school, for calculation of medical and nonmedical costs associated with illness.
RESULTS: One hundred thirty-five parents completed interviews between October 2005 and January 2006. Older children were significantly more likely to present with headache, compared with those < or = 5 years of age. No significant differences between older and younger children were found for rates of sore throat, fever, abdominal pain/nausea/vomiting, or rash. Children missed a mean of 1.9 days (range: 0-7 days) of school/day care, and 42% of parents missed a mean of 1.8 days of work. A second parent or caregiver also missed a mean of 1.5 days in 14% of families. The total societal cost per case of group A streptococcal pharyngitis was $205 (medical: $118; nonmedical: $87).
CONCLUSIONS: The societal cost of group A streptococcal pharyngitis is substantial, with almost one half being attributable to nonmedical costs. Through extrapolation from this experience, the total cost of group A streptococcal pharyngitis among children in the United States ranges from $224 to $539 million per year.

Entities:  

Mesh:

Year:  2008        PMID: 18245412     DOI: 10.1542/peds.2007-0484

Source DB:  PubMed          Journal:  Pediatrics        ISSN: 0031-4005            Impact factor:   7.124


  40 in total

1.  Retrospective study of group A Streptococcus oropharyngeal infection diagnosis using a rapid antigenic detection test in a paediatric population from the central region of Portugal.

Authors:  Nuno Mendes; Carmo Miguéis; Jorge Lindo; Teresa Gonçalves; António Miguéis
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2021-01-15       Impact factor: 3.267

2.  Streptococcus pyogenes emm Types and Clusters during a 7-Year Period (2007 to 2013) in Pharyngeal and Nonpharyngeal Pediatric Isolates.

Authors:  F Koutouzi; A Tsakris; P Chatzichristou; E Koutouzis; G L Daikos; E Kirikou; N Petropoulou; V Syriopoulou; A Michos
Journal:  J Clin Microbiol       Date:  2015-04-15       Impact factor: 5.948

3.  emm and C-repeat region molecular typing of beta-hemolytic Streptococci in a tropical country: implications for vaccine development.

Authors:  Andrew C Steer; Graham Magor; Adam W J Jenney; Joseph Kado; Michael F Good; David McMillan; Michael Batzloff; Jonathan R Carapetis
Journal:  J Clin Microbiol       Date:  2009-06-10       Impact factor: 5.948

4.  Evaluation of Simplexa Group A Strep Direct Kit Compared to Hologic Group A Streptococcal Direct Assay for Detection of Group A Streptococcus in Throat Swabs.

Authors:  Deirdre L Church; Tracie Lloyd; Oscar Larios; Daniel B Gregson
Journal:  J Clin Microbiol       Date:  2018-02-22       Impact factor: 5.948

Review 5.  Group A Streptococcus Testing in Pediatrics: the Move to Point-of-Care Molecular Testing.

Authors:  Thomas Z Thompson; Allison R McMullen
Journal:  J Clin Microbiol       Date:  2020-05-26       Impact factor: 5.948

6.  Impact of technical training on rapid antigen detection tests (RADT) in group A streptococcal tonsillopharyngitis.

Authors:  N Toepfner; P Henneke; R Berner; M Hufnagel
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2012-12-04       Impact factor: 3.267

7.  Molecular and clinical diagnosis of group A streptococcal pharyngitis in children.

Authors:  Susanna Felsenstein; Diala Faddoul; Richard Sposto; Kristine Batoon; Claudia M Polanco; Jennifer Dien Bard
Journal:  J Clin Microbiol       Date:  2014-08-20       Impact factor: 5.948

8.  Healthcare Utilization and Missed Workdays for Parents of Children With Traumatic Brain Injury.

Authors:  Richard E Nelson; Junjie Ma; Yan Cheng; Linda Ewing-Cobbs; Amy Clark; Heather Keenan
Journal:  J Head Trauma Rehabil       Date:  2019 Jul/Aug       Impact factor: 2.710

9.  Preferences for health outcomes associated with Group A Streptococcal disease and vaccination.

Authors:  Grace M Lee; Joshua A Salomon; Charlene Gay; James K Hammitt
Journal:  Health Qual Life Outcomes       Date:  2010-03-12       Impact factor: 3.186

10.  Multicenter clinical evaluation of the illumigene group A Streptococcus DNA amplification assay for detection of group A Streptococcus from pharyngeal swabs.

Authors:  Neil W Anderson; Blake W Buchan; Donna Mayne; Joel E Mortensen; Tami-Lea A Mackey; Nathan A Ledeboer
Journal:  J Clin Microbiol       Date:  2013-02-27       Impact factor: 5.948

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