BACKGROUND: Despite several case reports of sirolimus-eluting stent (SES) fracture and concern regarding restenosis after successful SES implantation, the clinical characteristics of this problem are not well known. METHODS: Clinical records and angiographic films of patients who received follow-up coronary angiography between February 2005 and October 2006 were retrospectively analyzed. RESULTS: Among the 686 SES implanted in 479 patients, 27 fractures were found in 22 (3.2%) stents in 18 patients. All stent fractures occurred in long stented segments, i.e. >/=28 mm (range, 28 mm to 83 mm). Of the 22 fractured stents, sixteen (72.7%) were identified in the right coronary artery (RCA) and fifteen (68.2%) were found to have a fracture site within 10 mm from areas with increased rigidity due to metal overlap. The significant multivariate predictors of stent fracture were the stented length (Odds ratio 1.06; 95% confidence interval 1.04-1.09; p=0.001) and the RCA location (Odds ratio 4.44; 95% confidence interval 1.66-11.86; p=0.003). The binary restenosis rate was 22.7% and target lesion revascularization was performed in two (9.1%) fractured stents. CONCLUSIONS: SES fracture was associated with a long stented segment, RCA location and metal overlap. Stent fracture may be another potential risk factor for restenosis after successful SES implantation.
BACKGROUND: Despite several case reports of sirolimus-eluting stent (SES) fracture and concern regarding restenosis after successful SES implantation, the clinical characteristics of this problem are not well known. METHODS: Clinical records and angiographic films of patients who received follow-up coronary angiography between February 2005 and October 2006 were retrospectively analyzed. RESULTS: Among the 686 SES implanted in 479 patients, 27 fractures were found in 22 (3.2%) stents in 18 patients. All stent fractures occurred in long stented segments, i.e. >/=28 mm (range, 28 mm to 83 mm). Of the 22 fractured stents, sixteen (72.7%) were identified in the right coronary artery (RCA) and fifteen (68.2%) were found to have a fracture site within 10 mm from areas with increased rigidity due to metal overlap. The significant multivariate predictors of stent fracture were the stented length (Odds ratio 1.06; 95% confidence interval 1.04-1.09; p=0.001) and the RCA location (Odds ratio 4.44; 95% confidence interval 1.66-11.86; p=0.003). The binary restenosis rate was 22.7% and target lesion revascularization was performed in two (9.1%) fractured stents. CONCLUSIONS:SESfracture was associated with a long stented segment, RCA location and metal overlap. Stent fracture may be another potential risk factor for restenosis after successful SES implantation.
Authors: Sun Hong Yoo; Seung Won Jin; Sung Ho Her; Hee Jeoung Yoon; Hyoung Doo Kim; Yun Sun Im; Ki Bae Seung; Jae Hyung Kim Journal: Korean Circ J Date: 2009-06-30 Impact factor: 3.243
Authors: Ali S Almasood; Xavier Freixa; Sohail Q Khan; Peter H Seidelin; Vladimír Džavík Journal: Cardiol Res Pract Date: 2011-04-03 Impact factor: 1.866
Authors: Frank J H Gijsen; Francesco Migliavacca; Silvia Schievano; Laura Socci; Lorenza Petrini; Attila Thury; Jolanda J Wentzel; Anton F W van der Steen; Patrick W S Serruys; Gabriele Dubini Journal: Biomed Eng Online Date: 2008-08-06 Impact factor: 2.819