Literature DB >> 18240877

Maladaptive behaviors related to dementia status in adults with Down syndrome.

Tiina K Urv1, Warren B Zigman, Wayne Silverman.   

Abstract

Changes in maladaptive behaviors related to specific stages of dementia were investigated in 251 adults 45 years of age and older with Down syndrome. Findings indicate clear differences in maladaptive behaviors at various stages of dementia. Generally, individuals with no signs or symptoms of dementia displayed fewer and less severe maladaptive behaviors than individuals in the early and mid-stages of dementia. Individuals transitioning into the early stages of dementia from no dementia displayed increased aggression, fearfulness, sadness, sleep problems, social inadequacy, stealing, and general regressive behavior. Thus, new concerns regarding these types of behaviors could be particularly useful in clarifying the dementia status of adults with Down syndrome and developing individualized plans for support.

Entities:  

Mesh:

Year:  2008        PMID: 18240877     DOI: 10.1352/0895-8017(2008)113[73:MBRTDS]2.0.CO;2

Source DB:  PubMed          Journal:  Am J Ment Retard        ISSN: 0895-8017


  13 in total

1.  Language Characteristics of Individuals with Down Syndrome.

Authors:  Gary E Martin; Jessica Klusek; Bruno Estigarribia; Joanne E Roberts
Journal:  Top Lang Disord       Date:  2009-04

2.  Alzheimer's Disease in Adults with Down Syndrome.

Authors:  Warren B Zigman; Darlynne A Devenny; Sharon J Krinsky-McHale; Edmund C Jenkins; Tiina K Urv; Jerzy Wegiel; Nicole Schupf; Wayne Silverman
Journal:  Int Rev Res Ment Retard       Date:  2008-01-01

3.  Outcome Measures for Clinical Trials in Down Syndrome.

Authors:  Anna J Esbensen; Stephen R Hooper; Deborah Fidler; Sigan L Hartley; Jamie Edgin; Xavier Liogier d'Ardhuy; George Capone; Frances A Conners; Carolyn B Mervis; Leonard Abbeduto; Michael Rafii; Sharon J Krinsky-McHale; Tiina Urv
Journal:  Am J Intellect Dev Disabil       Date:  2017-05

4.  Identifying dementia in Down syndrome with the Severe Impairment Battery, Brief Praxis Test and Dementia Scale for People with Learning Disabilities.

Authors:  E R Wallace; J P Harp; K L Van Pelt; L M Koehl; A M Caban-Holt; A J Anderson-Mooney; G A Jicha; D D Lightner; W C Robertson; E Head; F A Schmitt
Journal:  J Intellect Disabil Res       Date:  2021-11-16

5.  Differentiating Aging Among Adults With Down Syndrome and Comorbid Dementia or Psychopathology.

Authors:  Anna J Esbensen; Emily Boshkoff Johnson; Joseph L Amaral; Christine M Tan; Ryan Macks
Journal:  Am J Intellect Dev Disabil       Date:  2016-01

Review 6.  Clinical aspects and biomarkers of Alzheimer's disease in Down syndrome.

Authors:  Panagiotis Zis; Andre Strydom
Journal:  Free Radic Biol Med       Date:  2017-09-01       Impact factor: 7.376

Review 7.  The Early Presentation of Dementia in People with Down Syndrome: a Systematic Review of Longitudinal Studies.

Authors:  Bianca Alexandra Lautarescu; Anthony John Holland; Shahid H Zaman
Journal:  Neuropsychol Rev       Date:  2017-03-13       Impact factor: 7.444

8.  The Behavioral and Psychological Symptoms of Dementia in Down Syndrome (BPSD-DS) Scale: Comprehensive Assessment of Psychopathology in Down Syndrome.

Authors:  Alain D Dekker; Silvia Sacco; Angelo Carfi; Bessy Benejam; Yannick Vermeiren; Gonny Beugelsdijk; Mieke Schippers; Lyanne Hassefras; José Eleveld; Sharina Grefelman; Roelie Fopma; Monique Bomer-Veenboer; Mariángeles Boti; G Danielle E Oosterling; Esther Scholten; Marleen Tollenaere; Laura Checkley; André Strydom; Gert Van Goethem; Graziano Onder; Rafael Blesa; Christine Zu Eulenburg; Antonia M W Coppus; Anne-Sophie Rebillat; Juan Fortea; Peter P De Deyn
Journal:  J Alzheimers Dis       Date:  2018       Impact factor: 4.472

9.  Plasma neurofilament light chain: A potential prognostic biomarker of dementia in adult Down syndrome patients.

Authors:  Makiko Shinomoto; Takashi Kasai; Harutsugu Tatebe; Masaki Kondo; Takuma Ohmichi; Masafumi Morimoto; Tomohiro Chiyonobu; Naoto Terada; David Allsop; Isao Yokota; Toshiki Mizuno; Takahiko Tokuda
Journal:  PLoS One       Date:  2019-04-05       Impact factor: 3.240

10.  Toward onset prevention of cognitive decline in adults with Down syndrome (the TOP-COG study): study protocol for a randomized controlled trial.

Authors:  Sally-Ann Cooper; Muriel Caslake; Jonathan Evans; Angela Hassiotis; Andrew Jahoda; Alex McConnachie; Jill Morrison; Howard Ring; John Starr; Ciara Stiles; Frank Sullivan
Journal:  Trials       Date:  2014-06-03       Impact factor: 2.279

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