OBJECTIVE: To determine the factors associated with high-dose antipsychotic prescribing for psychiatric patients in Hong Kong. DESIGN: Retrospective cross-sectional study. SETTING: Psychiatric in-patients and out-patients in the New Territories West Cluster, Hong Kong. PATIENTS: A total of 1129 in-patients and 7520 out-patients who received antipsychotic medications on the study date. MAIN OUTCOME MEASURES: Demographic and clinical data were compared for patients receiving 'normal' and high dosages of antipsychotic medications. RESULTS: High dosages were prescribed for 104 (9.2%) of the in-patients and 137 (1.8%) of out-patients. Antipsychotic polypharmacy was the most powerful predictor of high-dose prescribing, with an odds ratio of 8.88 for in-patients and 10.82 for out-patients. CONCLUSION: Antipsychotic polypharmacy was the main determinant of high-dose antipsychotic prescribing in this study. Further studies should be conducted to look for other variables contributing to such prescribing in Hong Kong.
OBJECTIVE: To determine the factors associated with high-dose antipsychotic prescribing for psychiatricpatients in Hong Kong. DESIGN: Retrospective cross-sectional study. SETTING:Psychiatric in-patients and out-patients in the New Territories West Cluster, Hong Kong. PATIENTS: A total of 1129 in-patients and 7520 out-patients who received antipsychotic medications on the study date. MAIN OUTCOME MEASURES: Demographic and clinical data were compared for patients receiving 'normal' and high dosages of antipsychotic medications. RESULTS: High dosages were prescribed for 104 (9.2%) of the in-patients and 137 (1.8%) of out-patients. Antipsychotic polypharmacy was the most powerful predictor of high-dose prescribing, with an odds ratio of 8.88 for in-patients and 10.82 for out-patients. CONCLUSION: Antipsychotic polypharmacy was the main determinant of high-dose antipsychotic prescribing in this study. Further studies should be conducted to look for other variables contributing to such prescribing in Hong Kong.
Authors: Ihechiluru G Anozie; Bawo O James; Joyce O Omoaregba; Sunday O Oriji; Paul O Erohubie; Anthony C Enebe Journal: S Afr J Psychiatr Date: 2022-04-29 Impact factor: 1.242
Authors: Nitin Toteja; Juan A Gallego; Ema Saito; Tobias Gerhard; Almut Winterstein; Mark Olfson; Christoph U Correll Journal: Int J Neuropsychopharmacol Date: 2013-05-14 Impact factor: 5.176