OBJECTIVE: This study investigated the characteristics of cerebral oxygenation changes in eating disorders patients (ED) and normal controls during the cognitive tasks, using a highly time-resolved, and non-invasive instrument. METHOD: Eleven female patients with anorexia nervosa or bulimia nervosa were recruited, and 11 healthy females participated. The relative concentrations of oxy-hemoglobin [o-Hb] and deoxy-hemoglobin [d-Hb] were measured during word fluency task using multichannel near infrared spectroscopy (NIRS). RESULTS: The increases of o-Hb and d-Hb during the task were compared between the groups. ED patients showed lower activation and a gradual increase in o-HB during the task. In the frontal, d-HB concentrations decreased during the task in ED patients. CONCLUSION: These specific patterns of oxygenation changes may indicate less supply and less demand of cerebral blood volume. Bedside measurements of cerebral oxygenation changes using NIRS are useful on understanding of neurophysiological features of ED.
OBJECTIVE: This study investigated the characteristics of cerebral oxygenation changes in eating disorderspatients (ED) and normal controls during the cognitive tasks, using a highly time-resolved, and non-invasive instrument. METHOD: Eleven female patients with anorexia nervosa or bulimia nervosa were recruited, and 11 healthy females participated. The relative concentrations of oxy-hemoglobin [o-Hb] and deoxy-hemoglobin [d-Hb] were measured during word fluency task using multichannel near infrared spectroscopy (NIRS). RESULTS: The increases of o-Hb and d-Hb during the task were compared between the groups. ED patients showed lower activation and a gradual increase in o-HB during the task. In the frontal, d-HB concentrations decreased during the task in ED patients. CONCLUSION: These specific patterns of oxygenation changes may indicate less supply and less demand of cerebral blood volume. Bedside measurements of cerebral oxygenation changes using NIRS are useful on understanding of neurophysiological features of ED.
Authors: D Jannet Mehagnoul-Schipper; Bas F W van der Kallen; Willy N J M Colier; Marco C van der Sluijs; Leon J Th O van Erning; Henk O M Thijssen; Berend Oeseburg; Willibrord H L Hoefnagels; René W M M Jansen Journal: Hum Brain Mapp Date: 2002-05 Impact factor: 5.038
Authors: C M Gordon; D D Dougherty; A J Fischman; S J Emans; E Grace; R Lamm; N M Alpert; J A Majzoub; S L Rauch Journal: J Pediatr Date: 2001-07 Impact factor: 4.406
Authors: Antonio Maria Ferro; Andrea Brugnolo; Caterina De Leo; Barbara Dessi; Nicola Girtler; Silvia Morbelli; Flavio Nobili; Davide Sebastiano Rossi; Maria Falchero; Giovanni Murialdo; Paolo M Rossini; Claudio Babiloni; Rodolfo Schizzi; Riccardo Padolecchia; Guido Rodriguez Journal: Int J Eat Disord Date: 2005-12 Impact factor: 4.861
Authors: Rudolf Uher; Tara Murphy; Hans-Christoph Friederich; Tim Dalgleish; Michael J Brammer; Vincent Giampietro; Mary L Phillips; Christopher M Andrew; Virginia W Ng; Steven C R Williams; Iain C Campbell; Janet Treasure Journal: Biol Psychiatry Date: 2005-08-08 Impact factor: 13.382
Authors: D Val-Laillet; E Aarts; B Weber; M Ferrari; V Quaresima; L E Stoeckel; M Alonso-Alonso; M Audette; C H Malbert; E Stice Journal: Neuroimage Clin Date: 2015-03-24 Impact factor: 4.881