| Literature DB >> 18227181 |
Carolina Serena1, Marçal Mariné, Guillermo Quindós, Alfonso J Carrillo, J F Cano, F Javier Pastor, Josep Guarro.
Abstract
The in vitro activity of amphotericin B in combination with micafungin was evaluated against 115 isolates representing seven species of Candida. Overall, the percentages of synergistic interactions were 50% and 20% when the MIC-2 (lowest drug concentration to cause a prominent reduction in growth) and MIC-0 (lowest drug concentration to cause 100% growth inhibition) end point criteria, respectively, were used. Antagonism was not observed. Some of the interactions were confirmed by time-kill assays.Entities:
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Year: 2008 PMID: 18227181 PMCID: PMC2292525 DOI: 10.1128/AAC.01097-07
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191