Literature DB >> 18225988

The role of long non-coding RNAs in chromatin structure and gene regulation: variations on a theme.

David Umlauf1, Peter Fraser, Takashi Nagano.   

Abstract

Transcriptome studies have uncovered a plethora of noncoding RNAs (ncRNA) in mammals. Most originate within intergenic regions of the genome and recent evidence indicates that some are involved in many different pathways that ultimately act on genome architecture and gene expression. In this review, we discuss the role of well-characterized long ncRNAs in gene regulation pointing to their similarities, but also their differences. We will attempt to highlight a paradoxical situation in which transcription is needed to repress entire chromosomal domains possibly through the action of ncRNAs that create nuclear environments refractory to transcription.

Mesh：

Substances：

Year:  2008        PMID： 18225988     DOI： 10.1515/BC.2008.047

Source DB:  PubMed          Journal:  Biol Chem        ISSN： 1431-6730            Impact factor:   3.915


  31 in total

Review 1.  The long arm of long noncoding RNAs: roles as sensors regulating gene transcriptional programs.

Authors:  Xiangting Wang; Xiaoyuan Song; Christopher K Glass; Michael G Rosenfeld
Journal:  Cold Spring Harb Perspect Biol       Date:  2011-01-01       Impact factor: 10.005

2.  The long noncoding RNA Kcnq1ot1 organises a lineage-specific nuclear domain for epigenetic gene silencing.

Authors:  Lisa Redrup; Miguel R Branco; Elizabeth R Perdeaux; Christel Krueger; Annabelle Lewis; Fátima Santos; Takashi Nagano; Bradley S Cobb; Peter Fraser; Wolf Reik
Journal:  Development       Date:  2009-01-14       Impact factor: 6.868

Review 3.  Emerging similarities in epigenetic gene silencing by long noncoding RNAs.

Authors:  Takashi Nagano; Peter Fraser
Journal:  Mamm Genome       Date:  2009-09-01       Impact factor: 2.957

4.  Avian sex chromosomes: dosage compensation matters.

Authors:  Heather A McQueen; Michael Clinton
Journal:  Chromosome Res       Date:  2009       Impact factor: 5.239

5.  Molecular interplay of the noncoding RNA ANRIL and methylated histone H3 lysine 27 by polycomb CBX7 in transcriptional silencing of INK4a.

Authors:  Kyoko L Yap; Side Li; Ana M Muñoz-Cabello; Selina Raguz; Lei Zeng; Shiraz Mujtaba; Jesús Gil; Martin J Walsh; Ming-Ming Zhou
Journal:  Mol Cell       Date:  2010-06-11       Impact factor: 17.970

6.  The Xist lncRNA exploits three-dimensional genome architecture to spread across the X chromosome.

Authors:  Jesse M Engreitz; Amy Pandya-Jones; Patrick McDonel; Alexander Shishkin; Klara Sirokman; Christine Surka; Sabah Kadri; Jeffrey Xing; Alon Goren; Eric S Lander; Kathrin Plath; Mitchell Guttman
Journal:  Science       Date:  2013-07-04       Impact factor: 47.728

7.  Topological organization of multichromosomal regions by the long intergenic noncoding RNA Firre.

Authors:  Ezgi Hacisuleyman; Loyal A Goff; Cole Trapnell; Adam Williams; Jorge Henao-Mejia; Lei Sun; Patrick McClanahan; David G Hendrickson; Martin Sauvageau; David R Kelley; Michael Morse; Jesse Engreitz; Eric S Lander; Mitch Guttman; Harvey F Lodish; Richard Flavell; Arjun Raj; John L Rinn
Journal:  Nat Struct Mol Biol       Date:  2014-01-26       Impact factor: 15.369

Review 8.  Chromatin mechanisms in genomic imprinting.

Authors:  Slim Kacem; Robert Feil
Journal:  Mamm Genome       Date:  2009-09-17       Impact factor: 2.957

Review 9.  Noncoding RNA control of cellular senescence.

Authors:  Kotb Abdelmohsen; Myriam Gorospe
Journal:  Wiley Interdiscip Rev RNA       Date:  2015-09-01       Impact factor: 9.957

10.  An intergenic non-coding rRNA correlated with expression of the rRNA and frequency of an rRNA single nucleotide polymorphism in lung cancer cells.

Authors:  Yih-Horng Shiao; Sorin T Lupascu; Yuhan D Gu; Wojciech Kasprzak; Christopher J Hwang; Janet R Fields; Robert M Leighty; Octavio Quiñones; Bruce A Shapiro; W Gregory Alvord; Lucy M Anderson
Journal:  PLoS One       Date:  2009-10-19       Impact factor: 3.240
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.