Literature DB >> 18223542

The aging hypertensive heart: a brief update.

Dinko Susic1, Edward D Frohlich.   

Abstract

Hypertension and aging are major independent risk factors for cardiovascular-related morbidity and mortality. Although independent, these two entities are closely related and operate simultaneously to adversely affect the cardiovascular system. In many aspects the morphologic and functional changes that occur in the cardiovascular system with aging and hypertension are similar; both include left ventricular hypertrophy, fibrosis and dysfunction. In this report we briefly summarize the primary pathophysiology of cardiovascular aging and hypertension and describe the clinical and therapeutic impact that hypertension and aging combined have on the cardiovascular system.

Entities:  

Mesh：

Substances：

Year:  2008        PMID： 18223542     DOI： 10.1038/ncpcardio1091

Source DB:  PubMed          Journal:  Nat Clin Pract Cardiovasc Med        ISSN： 1743-4297


  14 in total

Review 1.  Age-related cardiovascular disease and the beneficial effects of calorie restriction.

Authors:  Miranda M Y Sung; Jason R B Dyck
Journal:  Heart Fail Rev       Date:  2012-09       Impact factor: 4.214

Review 2.  The aging heart and post-infarction left ventricular remodeling.

Authors:  Henry Shih; Brian Lee; Randall J Lee; Andrew J Boyle
Journal:  J Am Coll Cardiol       Date:  2011-01-04       Impact factor: 24.094

Review 3.  K(ATP) channel-dependent metaboproteome decoded: systems approaches to heart failure prediction, diagnosis, and therapy.

Authors:  D Kent Arrell; Jelena Zlatkovic Lindor; Satsuki Yamada; Andre Terzic
Journal:  Cardiovasc Res       Date:  2011-02-14       Impact factor: 10.787

4.  Inactivation of endothelial proprotein convertase 5/6 decreases collagen deposition in the cardiovascular system: role of fibroblast autophagy.

Authors:  Chiara Marchesi; Rachid Essalmani; Catherine A Lemarié; Eyal Leibovitz; Talin Ebrahimian; Pierre Paradis; Nabil G Seidah; Ernesto L Schiffrin; Annik Prat
Journal:  J Mol Med (Berl)       Date:  2011-06-17       Impact factor: 4.599

5.  Marinobufagenin-induced vascular fibrosis is a likely target for mineralocorticoid antagonists.

Authors:  Olga V Fedorova; Igor V Emelianov; Konstantin A Bagrov; Yulia N Grigorova; Wen Wei; Ondrej Juhasz; Elena V Frolova; Courtney A Marshall; Edward G Lakatta; Alexandra O Konradi; Alexei Y Bagrov
Journal:  J Hypertens       Date:  2015-08       Impact factor: 4.844

6.  Thioredoxin reverses age-related hypertension by chronically improving vascular redox and restoring eNOS function.

Authors:  Rob H P Hilgers; Venkatesh Kundumani-Sridharan; Jaganathan Subramani; Leon C Chen; Luis G Cuello; Nancy J Rusch; Kumuda C Das
Journal:  Sci Transl Med       Date:  2017-02-08       Impact factor: 17.956

Review 7.  Pathological ventricular remodeling: mechanisms: part 1 of 2.

Authors:  Jana S Burchfield; Min Xie; Joseph A Hill
Journal:  Circulation       Date:  2013-07-23       Impact factor: 29.690

8.  Metabolic dysfunction consistent with premature aging results from deletion of Pim kinases.

Authors:  Shabana Din; Mathias H Konstandin; Bevan Johnson; Jacqueline Emathinger; Mirko Völkers; Haruhiro Toko; Brett Collins; Lucy Ormachea; Kaitlen Samse; Dieter A Kubli; Andrea De La Torre; Andrew S Kraft; Asa B Gustafsson; Daniel P Kelly; Mark A Sussman
Journal:  Circ Res       Date:  2014-06-10       Impact factor: 17.367

9.  Age-associated increase in salt sensitivity is accompanied by a shift in the atrial natriuretic peptide modulation of the effect of marinobufagenin on renal and vascular sodium pump.

Authors:  Olga V Fedorova; Vladimir A Kashkin; Irina O Zakharova; Edward G Lakatta; Alexei Y Bagrov
Journal:  J Hypertens       Date:  2012-09       Impact factor: 4.844

10.  Structural remodelling of the sinoatrial node in obese old rats.

Authors:  J Yanni; J O Tellez; P V Sutyagin; M R Boyett; H Dobrzynski
Journal:  J Mol Cell Cardiol       Date:  2009-09-01       Impact factor: 5.000
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.