| Literature DB >> 18223526 |
Jose V Bagan1, Yolanda Jiménez, Judith Murillo, Rafael Poveda, José M Díaz, Carmen Gavaldá, María Margaix, Crispian Scully, Trinidad M Alberola, Manuela Torres Puente, Manuel Pérez Alonso.
Abstract
The aim of this study was to analyze proliferative verrucous leukoplakia (PVL) and oral squamous cell carcinoma (OSCC) for the possible presence of Epstein-Barr virus (EBV). We studied three groups: Sub-Group 1 was composed of 10 patients with PVL, (6 of whom had developed OSCC); Sub-Group 2 comprised 5 patients with OSCC but no preceding PVL; and Sub-Group 3 were 5 controls with clinically normal oral mucosa. Oral biopsies from all cases were examined for Epstein-Barr virus (EBV) by nested PCR. EBV was detected in 60% of Sub-Group 1 patients (PVL ) and in 40% of Sub-Group 2 (OSCC), but in 0% of Sub-Group 3 (controls).Entities:
Mesh：
Year: 2008 PMID： 18223526
Source DB: PubMed Journal: Med Oral Patol Oral Cir Bucal ISSN： 1698-4447