| Literature DB >> 25553134 |
Ioanina Parlatescu1, Carmen Gheorghe1, Elena Coculescu2, Serban Tovaru1.
Abstract
ABSTRACT: The main purpose of this paper was to assess the current state of science on oral leukoplakia. Although it is considered a potentially malignant disorder the overall malignant progression of oral leukoplakia is of the order of 5% and even more. Nowadays there are no currently accepted markers to distinguish those that may progress to cancer from those that may not. The current golden standard is considered the presence of epithelial dysplasia on the tissue biopsy of the lesion. Proliferative verrucous leukoplakia is a rare form of OL which has multiple recurrences, is refractory to treatment and has malignant transformation in a short period. It is considered a true premalignant lesion. The management of oral leukoplakia varies from a "wait and see" attitude and topical chemopreventive agents to complete surgical removal.Entities:
Keywords: oral leukoplakia; potentially malignant disorder
Year: 2014 PMID: 25553134 PMCID: PMC4268300
Source DB: PubMed Journal: Maedica (Buchar) ISSN: 1841-9038