Literature DB >> 18223003

Sedimentation studies on human amylin fail to detect low-molecular-weight oligomers.

Sara M Vaiana, Rodolfo Ghirlando, Wai-Ming Yau, William A Eaton, James Hofrichter.   

Abstract

Sedimentation velocity experiments show that only monomers coexist with amyloid fibrils of human islet amyloid-polypeptide. No oligomers containing <100 monomers could be detected, suggesting that the putative toxic oligomers are much larger than those found for the Alzheimer's peptide, Abeta(1-42).

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Year:  2008        PMID： 18223003      PMCID： PMC2267115          DOI： 10.1529/biophysj.107.125146

Source DB:  PubMed          Journal:  Biophys J        ISSN： 0006-3495            Impact factor:   4.033


  27 in total

1.  Structural studies of soluble oligomers of the Alzheimer beta-amyloid peptide.

Authors:  T H Huang; D S Yang; N P Plaskos; S Go; C M Yip; P E Fraser; A Chakrabartty
Journal:  J Mol Biol       Date:  2000-03-17       Impact factor: 5.469

Review 2.  Islet amyloid and type 2 diabetes: from molecular misfolding to islet pathophysiology.

Authors:  E T Jaikaran; A Clark
Journal:  Biochim Biophys Acta       Date:  2001-11-29

3.  Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis.

Authors:  Rakez Kayed; Elizabeth Head; Jennifer L Thompson; Theresa M McIntire; Saskia C Milton; Carl W Cotman; Charles G Glabe
Journal:  Science       Date:  2003-04-18       Impact factor: 47.728

Review 4.  Protofibrils, pores, fibrils, and neurodegeneration: separating the responsible protein aggregates from the innocent bystanders.

Authors:  Byron Caughey; Peter T Lansbury
Journal:  Annu Rev Neurosci       Date:  2003-04-09       Impact factor: 12.449

5.  Human amylin oligomer growth and fibril elongation define two distinct phases in amyloid formation.

Authors:  Janelle D Green; Claire Goldsbury; Joerg Kistler; Garth J S Cooper; Ueli Aebi
Journal:  J Biol Chem       Date:  2004-01-01       Impact factor: 5.157

Review 6.  From the polymorphism of amyloid fibrils to their assembly mechanism and cytotoxicity.

Authors:  Laurent Kreplak; Ueli Aebi
Journal:  Adv Protein Chem       Date:  2006

7.  Purification and characterization of a peptide from amyloid-rich pancreases of type 2 diabetic patients.

Authors:  G J Cooper; A C Willis; A Clark; R C Turner; R B Sim; K B Reid
Journal:  Proc Natl Acad Sci U S A       Date:  1987-12       Impact factor: 11.205

8.  Amyloid fibrils in human insulinoma and islets of Langerhans of the diabetic cat are derived from a neuropeptide-like protein also present in normal islet cells.

Authors:  P Westermark; C Wernstedt; E Wilander; D W Hayden; T D O'Brien; K H Johnson
Journal:  Proc Natl Acad Sci U S A       Date:  1987-06       Impact factor: 11.205

Review 9.  Amyloidogenicity and cytotoxicity of islet amyloid polypeptide.

Authors:  A Kapurniotu
Journal:  Biopolymers       Date:  2001       Impact factor: 2.505

10.  Structural characterisation of islet amyloid polypeptide fibrils.

Authors:  O Sumner Makin; Louise C Serpell
Journal:  J Mol Biol       Date:  2004-01-30       Impact factor: 5.469
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  18 in total

1.  How type II diabetes-related islet amyloid polypeptide damages lipid bilayers.

Authors:  Chang-Chun Lee; Yen Sun; Huey W Huang
Journal:  Biophys J       Date:  2012-03-06       Impact factor: 4.033

2.  Membrane disruption and early events in the aggregation of the diabetes related peptide IAPP from a molecular perspective.

Authors:  Jeffrey R Brender; Samer Salamekh; Ayyalusamy Ramamoorthy
Journal:  Acc Chem Res       Date:  2011-09-25       Impact factor: 22.384

3.  The molecular basis of distinct aggregation pathways of islet amyloid polypeptide.

Authors:  Lei Wei; Ping Jiang; Weixin Xu; Hai Li; Hua Zhang; Liangyu Yan; Mary B Chan-Park; Xue-Wei Liu; Kai Tang; Yuguang Mu; Konstantin Pervushin
Journal:  J Biol Chem       Date:  2010-12-10       Impact factor: 5.157

4.  Biphasic effects of insulin on islet amyloid polypeptide membrane disruption.

Authors:  Jeffrey R Brender; Edgar L Lee; Kevin Hartman; Pamela T Wong; Ayyalusamy Ramamoorthy; Duncan G Steel; Ari Gafni
Journal:  Biophys J       Date:  2011-02-02       Impact factor: 4.033

5.  Evidence for a partially structured state of the amylin monomer.

Authors:  Sara M Vaiana; Robert B Best; Wai-Ming Yau; William A Eaton; James Hofrichter
Journal:  Biophys J       Date:  2009-12-02       Impact factor: 4.033

Review 6.  Toxic oligomers and islet beta cell death: guilty by association or convicted by circumstantial evidence?

Authors:  S Zraika; R L Hull; C B Verchere; A Clark; K J Potter; P E Fraser; D P Raleigh; S E Kahn
Journal:  Diabetologia       Date:  2010-02-25       Impact factor: 10.122

7.  Alternative pathways of human islet amyloid polypeptide aggregation distinguished by (19)f nuclear magnetic resonance-detected kinetics of monomer consumption.

Authors:  Yuta Suzuki; Jeffrey R Brender; Kevin Hartman; Ayyalusamy Ramamoorthy; E Neil G Marsh
Journal:  Biochemistry       Date:  2012-10-01       Impact factor: 3.162

8.  Phosphatidylethanolamine enhances amyloid fiber-dependent membrane fragmentation.

Authors:  Michele F M Sciacca; Jeffrey R Brender; Dong-Kuk Lee; Ayyalusamy Ramamoorthy
Journal:  Biochemistry       Date:  2012-09-21       Impact factor: 3.162

Review 9.  Islet amyloid: from fundamental biophysics to mechanisms of cytotoxicity.

Authors:  Ping Cao; Peter Marek; Harris Noor; Vadim Patsalo; Ling-Hsien Tu; Hui Wang; Andisheh Abedini; Daniel P Raleigh
Journal:  FEBS Lett       Date:  2013-02-01       Impact factor: 4.124

10.  Resolution of oligomeric species during the aggregation of Aβ1-40 using (19)F NMR.

Authors:  Yuta Suzuki; Jeffrey R Brender; Molly T Soper; Janarthanan Krishnamoorthy; Yunlong Zhou; Brandon T Ruotolo; Nicholas A Kotov; Ayyalusamy Ramamoorthy; E Neil G Marsh
Journal:  Biochemistry       Date:  2013-03-08       Impact factor: 3.162
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