Iterative reconstruction methods using regularization and optimal current patterns in electrical impedance tomography.

An iterative reconstruction method which minimizes the effects of ill-conditioning is discussed. Based on the modified Newton-Raphson algorithm, a regularization method which integrates prior information into the image reconstruction was developed. This improves the conditioning of the information matrix in the modified Newton-Raphson algorithm. Optimal current patterns were used to obtain voltages with maximal signal-to-noise ratio (SNR). A complete finite element model (FEM) was used for both the internal and the boundary electric fields. Reconstructed images from phantom data show that the use of regularization optimal current patterns, and a complete FEM model improves image accuracy. The authors also investigated factors affecting the image quality of the iterative algorithm such as the initial guess, image iteration, and optimal current updating.