Literature DB >> 18214501

[Typing, grading and staging of osteoarthritis: histopathological assessment of joint degeneration].

T Aigner1, S Söder.   

Abstract

Osteoarthritis (degenerative arthropathy) is one of the most common diseases particular in the elderly. Osteoarthritis can principally affect all joints, although the knee, hip and phalangeal joints are most commonly involved in a clinically relevant manner. The grading and classification of changes during cartilage degeneration is complex and only partly informative for clinical management. Overall, the process of joint destruction can always be evaluated for the pathogenesis ("typing"), extent ("staging") and the degree of focal damage ("grading"). However, particularly in the final stages of the disease (e. g. in connection with prosthetic surgery) a description and report should be limited to only the most essential features, because no specific clinical relevance exists for further evaluation. Only the identification of secondary types of degenerative changes, due to as yet unknown rheumatoid diseases, gout or extensive osteonecrosis is of particular interest to clinical colleagues (i.e. typing of the joint lesion).

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Mesh:

Year:  2008        PMID: 18214501     DOI: 10.1007/s00393-007-0249-2

Source DB:  PubMed          Journal:  Z Rheumatol        ISSN: 0340-1855            Impact factor:   1.372


  24 in total

Review 1.  Cell death in cartilage.

Authors:  K Kühn; D D D'Lima; S Hashimoto; M Lotz
Journal:  Osteoarthritis Cartilage       Date:  2004-01       Impact factor: 6.576

2.  Subtyping of osteoarthritic synoviopathy.

Authors:  S Oehler; D Neureiter; C Meyer-Scholten; T Aigner
Journal:  Clin Exp Rheumatol       Date:  2002 Sep-Oct       Impact factor: 4.473

Review 3.  Structure and function of cartilage collagens.

Authors:  P Bruckner; M van der Rest
Journal:  Microsc Res Tech       Date:  1994-08-01       Impact factor: 2.769

4.  Osteoarthritis cartilage histopathology: grading and staging.

Authors:  K P H Pritzker; S Gay; S A Jimenez; K Ostergaard; J-P Pelletier; P A Revell; D Salter; W B van den Berg
Journal:  Osteoarthritis Cartilage       Date:  2005-10-19       Impact factor: 6.576

5.  Independent expression of fibril-forming collagens I, II, and III in chondrocytes of human osteoarthritic cartilage.

Authors:  T Aigner; W Bertling; H Stöss; G Weseloh; K von der Mark
Journal:  J Clin Invest       Date:  1993-03       Impact factor: 14.808

Review 6.  Aging theories of primary osteoarthritis: from epidemiology to molecular biology.

Authors:  T Aigner; J Rose; J Martin; J Buckwalter
Journal:  Rejuvenation Res       Date:  2004       Impact factor: 4.663

7.  Morphologic alterations of the subchondral bone in advanced degenerative arthritis.

Authors:  J W Milgram
Journal:  Clin Orthop Relat Res       Date:  1983-03       Impact factor: 4.176

8.  Cluster analysis and display of genome-wide expression patterns.

Authors:  M B Eisen; P T Spellman; P O Brown; D Botstein
Journal:  Proc Natl Acad Sci U S A       Date:  1998-12-08       Impact factor: 11.205

9.  Activation of collagen type II expression in osteoarthritic and rheumatoid cartilage.

Authors:  T Aigner; H Stöss; G Weseloh; G Zeiler; K von der Mark
Journal:  Virchows Arch B Cell Pathol Incl Mol Pathol       Date:  1992

10.  Mechanisms of disease: role of chondrocytes in the pathogenesis of osteoarthritis--structure, chaos and senescence.

Authors:  Thomas Aigner; Stefan Söder; Pia M Gebhard; Audrey McAlinden; Jochen Haag
Journal:  Nat Clin Pract Rheumatol       Date:  2007-07
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  2 in total

1.  The elusive path to cartilage regeneration.

Authors:  Ernst B Hunziker
Journal:  Adv Mater       Date:  2009-09-04       Impact factor: 30.849

2.  Proposal for a New Histological Scoring System for Cartilage Repair.

Authors:  Maria Clara Ponce; Alessandro Rozim Zorzi; João Batista de Miranda; Eliane Maria Ingrid Amstalden
Journal:  Clinics (Sao Paulo)       Date:  2018-11-29       Impact factor: 2.365

  2 in total

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