Literature DB >> 18209131

Nonsteroidal anti-inflammatory drugs and postoperative bleeding following adenotonsillectomy in pediatric patients.

Anita Jeyakumar1, Todd M Brickman, Mary E Williamson, Keiko Hirose, Paul Krakovitz, Kenneth Whittemore, Christopher Discolo.   

Abstract

OBJECTIVE: To assess the effects of nonsteroidal anti-inflammatory drugs (NSAIDs) on bleeding for pediatric adenotonsillectomy in a retrospective study, based on the common practices at 2 different tertiary care facilities.
DESIGN: A retrospective study.
SETTING: Two different tertiary care facilities. PATIENTS: Children up to 16 years of age, who underwent elective adenotonsillectomy or tonsillectomy, were included in the study. All indications for adenotonsillectomy, and all surgical techniques were included. Children with a bleeding tendency, and those with contraindications to the use of NSAIDs (eg, because of allergy), were excluded from the study.
INTERVENTIONS: Nonsteroidal anti-inflammatory drugs. MAIN OUTCOME MEASURE: Postoperative bleeding in patients.
RESULTS: A total of 1160 patients were selected who met the criteria: 673 patients underwent an adenotonsillectomy or tonsillectomy and did not receive any preoperative and postoperative ibuprofen, and 487 patients underwent routine adenotonsillectomy or tonsillectomy and were given postoperative ibuprofen. We noted a 0.7% postoperative bleeding rate in patients who were not allowed to take ibuprofen perioperatively. There was a 1.0% postoperative bleeding rate in patients who were allowed to take ibuprofen perioperatively (P = .75).
CONCLUSION: Ibuprofen is not a contraindication to adenotonsillectomy or tonsillectomy and should be used in the control of postoperative pain if it is indicated in the patient.

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Year:  2008        PMID: 18209131     DOI: 10.1001/archoto.2007.11

Source DB:  PubMed          Journal:  Arch Otolaryngol Head Neck Surg        ISSN: 0886-4470


  8 in total

1.  The effect of ibuprofen on postoperative hemorrhage following tonsillectomy in children.

Authors:  Huseyin Yaman; Abdullah Belada; Suleyman Yilmaz
Journal:  Eur Arch Otorhinolaryngol       Date:  2010-10-02       Impact factor: 2.503

Review 2.  Nonsteroidal anti-inflammatory drugs and perioperative bleeding in paediatric tonsillectomy.

Authors:  Sharon R Lewis; Amanda Nicholson; Mary E Cardwell; Gretchen Siviter; Andrew F Smith
Journal:  Cochrane Database Syst Rev       Date:  2013-07-18

3.  [Not Available].

Authors:  Julie Rivard; Lavina Yu; Stéphanie Tremblay; Denis Lebel
Journal:  Can J Hosp Pharm       Date:  2016-06-30

4.  Occurrence of coagulation factor deficiency in post-tonsillectomy hemorrhage.

Authors:  Michaela Zumtobel; Klemens Frei
Journal:  Wien Klin Wochenschr       Date:  2011-04-11       Impact factor: 1.704

5.  [Pediatric perioperative systemic pain therapy: Austrian interdisciplinary recommendations on pediatric perioperative pain management].

Authors:  B Messerer; G Grögl; W Stromer; W Jaksch
Journal:  Schmerz       Date:  2014-02       Impact factor: 1.107

6.  Pain therapy in children and adolescents.

Authors:  Boris Zernikow; Tanja Hechler
Journal:  Dtsch Arztebl Int       Date:  2008-07-14       Impact factor: 5.594

7.  Effect of Paracetamol versus Ibuprofen in Adenotonsillectomy.

Authors:  Fatemeh Mirashrafi; Fatemeh Tavakolnejad; Behrooz Amirzargar; Arezou Abasi; Amin Amali
Journal:  Iran J Otorhinolaryngol       Date:  2021-11

8.  Lornoxicam versus tramadol for post-operative pain relief in patients undergoing ENT procedures.

Authors:  Ashraf A Abdelhalim; Sami Al Harethy; Mohamed Moustafa
Journal:  Saudi J Anaesth       Date:  2014-01
  8 in total

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