Literature DB >> 20890608

The effect of ibuprofen on postoperative hemorrhage following tonsillectomy in children.

Huseyin Yaman1, Abdullah Belada, Suleyman Yilmaz.   

Abstract

The objective of the study was to evaluate the effect of ibuprofen on hemorrhage after tonsillectomy in children. All charts of children, who underwent tonsillectomy with or without adenoidectomy, were reviewed. The age at the time of surgery ranged between 3 and 16 years (mean age = 7.55 ± 3.01 years). Children were divided into two groups based on the drugs used for postoperative pain relief. Group I received paracetamol after surgery. Group II received ibuprofen after surgery. A total of 62 patients received ibuprofen and 109 patients were given paracetamol. Post-tonsillectomy hemorrhage occurred in seven (4.1%) children, primary hemorrhage was noted in five patients and secondary hemorrhage occurred in two patients. While 3 of 62 children (4.8%) who were given ibuprofen had postoperative hemorrhage, 4 of 109 patients (3.7%) who were given paracetamol had hemorrhage There was no significant difference in hemorrhage rates between these two groups (p > 0.05). Hemorrhage following tonsillectomy is rare and frequently occurs in the early postoperative period. There is no significant increased risk of hemorrhage after ibuprofen administration and it can be used safely for post-tonsillectomy pain relief.

Entities:  

Mesh:

Substances:

Year:  2010        PMID: 20890608     DOI: 10.1007/s00405-010-1393-x

Source DB:  PubMed          Journal:  Eur Arch Otorhinolaryngol        ISSN: 0937-4477            Impact factor:   2.503


  21 in total

1.  Effect of ketorolac on bleeding time and postoperative pain in children: a double-blind, placebo-controlled comparison with meperidine.

Authors:  J D Bean-Lijewski; R D Hunt
Journal:  J Clin Anesth       Date:  1996-02       Impact factor: 9.452

2.  Effects of postoperative, nonsteroidal, antiinflammatory drugs on bleeding risk after tonsillectomy: meta-analysis of randomized, controlled trials.

Authors:  Emmanuel Marret; Antoine Flahault; Charles-Marc Samama; Francis Bonnet
Journal:  Anesthesiology       Date:  2003-06       Impact factor: 7.892

Review 3.  Nonsteroidal antiinflammatory drugs and the risk of operative site bleeding after tonsillectomy: a quantitative systematic review.

Authors:  Steen Møiniche; Janne Rømsing; Jørgen B Dahl; Martin R Tramèr
Journal:  Anesth Analg       Date:  2003-01       Impact factor: 5.108

4.  Post-tonsillectomy haemorrhage: a retrospective comparison of abscess- and elective tonsillectomy.

Authors:  G Lehnerdt; K Senska; K Jahnke; M Fischer
Journal:  Acta Otolaryngol       Date:  2005-12       Impact factor: 1.494

5.  Post-tonsillectomy hemorrhage: an assessment of risk factors.

Authors:  D Myssiorek; A Alvi
Journal:  Int J Pediatr Otorhinolaryngol       Date:  1996-09       Impact factor: 1.675

6.  Comparative study of diclofenac sodium and paracetamol for treatment of pain after adenotonsillectomy in children.

Authors:  M I Tawalbeh; O O Nawasreh; A M Husban
Journal:  Saudi Med J       Date:  2001-02       Impact factor: 1.484

7.  Post-tonsillectomy bleeding: a regional hospital experience.

Authors:  R B Ali; D Smyth; R Kane; M Donnelly
Journal:  Ir J Med Sci       Date:  2008-10-25       Impact factor: 1.568

8.  Serious post-tonsillectomy hemorrhage with and without lethal outcome in children and adolescents.

Authors:  J P Windfuhr; G Schloendorff; D Baburi; B Kremer
Journal:  Int J Pediatr Otorhinolaryngol       Date:  2008-05-02       Impact factor: 1.675

9.  Post-tonsillectomy hemorrhage rates: are they technique-dependent?

Authors:  Paul Walker; Donna Gillies
Journal:  Otolaryngol Head Neck Surg       Date:  2007-04       Impact factor: 3.497

10.  Benchmarking surgery: secondary post-tonsillectomy hemorrhage 1999-2005.

Authors:  Kari Jorunn Kvaerner
Journal:  Acta Otolaryngol       Date:  2009-02       Impact factor: 1.494

View more
  5 in total

Review 1.  Steroids for improving recovery following tonsillectomy in children.

Authors:  David L Steward; Jedidiah Grisel; Jareen Meinzen-Derr
Journal:  Cochrane Database Syst Rev       Date:  2011-08-10

Review 2.  Nonsteroidal anti-inflammatory drugs and perioperative bleeding in paediatric tonsillectomy.

Authors:  Sharon R Lewis; Amanda Nicholson; Mary E Cardwell; Gretchen Siviter; Andrew F Smith
Journal:  Cochrane Database Syst Rev       Date:  2013-07-18

3.  [Not Available].

Authors:  Julie Rivard; Lavina Yu; Stéphanie Tremblay; Denis Lebel
Journal:  Can J Hosp Pharm       Date:  2016-06-30

4.  [Pediatric perioperative systemic pain therapy: Austrian interdisciplinary recommendations on pediatric perioperative pain management].

Authors:  B Messerer; G Grögl; W Stromer; W Jaksch
Journal:  Schmerz       Date:  2014-02       Impact factor: 1.107

5.  In silico analysis suggests repurposing of ibuprofen for prevention and treatment of EBOLA virus disease.

Authors:  Veljko Veljkovic; Marco Goeijenbier; Sanja Glisic; Nevena Veljkovic; Vladimir R Perovic; Milan Sencanski; Donald R Branch; Slobodan Paessler
Journal:  F1000Res       Date:  2015-05-01
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.