PURPOSE: To integrate PET-CT scans from different hospitals into radiotherapy treatment planning. METHODS AND MATERIALS: A cylindrical phantom with spheres of different diameters was scanned on three different Siemens Biograph PET-CT scanners in three hospitals. The spheres and cylinder were filled with 18F-FDG such that different sphere-to-background (S/B) ratios were obtained. Scans were analyzed using dedicated software for automated delineation based on standardized uptake value (SUV) and using different reconstruction parameters. RESULTS: SUV thresholding curves for different S/B ratios were obtained for the different scanners. Differences in SUV auto-contouring thresholds were found to be significant for PET-CT simulators from different radiotherapy and nuclear medicine departments. A change in PET reconstruction parameters showed a significant effect on the results. CONCLUSION: Synchronization of PET-CT imaging protocols between cooperating hospitals is important for reliable determination of SUV auto-contouring thresholds. Whenever this goal has been achieved automated SUV delineation based on a S/B ratio using PET-CT images from different institutions can reliably be performed using individually determined threshold curves.
PURPOSE: To integrate PET-CT scans from different hospitals into radiotherapy treatment planning. METHODS AND MATERIALS: A cylindrical phantom with spheres of different diameters was scanned on three different Siemens Biograph PET-CT scanners in three hospitals. The spheres and cylinder were filled with 18F-FDG such that different sphere-to-background (S/B) ratios were obtained. Scans were analyzed using dedicated software for automated delineation based on standardized uptake value (SUV) and using different reconstruction parameters. RESULTS: SUV thresholding curves for different S/B ratios were obtained for the different scanners. Differences in SUV auto-contouring thresholds were found to be significant for PET-CT simulators from different radiotherapy and nuclear medicine departments. A change in PET reconstruction parameters showed a significant effect on the results. CONCLUSION: Synchronization of PET-CT imaging protocols between cooperating hospitals is important for reliable determination of SUV auto-contouring thresholds. Whenever this goal has been achieved automated SUV delineation based on a S/B ratio using PET-CT images from different institutions can reliably be performed using individually determined threshold curves.
Authors: Mathieu Hatt; John A Lee; Charles R Schmidtlein; Issam El Naqa; Curtis Caldwell; Elisabetta De Bernardi; Wei Lu; Shiva Das; Xavier Geets; Vincent Gregoire; Robert Jeraj; Michael P MacManus; Osama R Mawlawi; Ursula Nestle; Andrei B Pugachev; Heiko Schöder; Tony Shepherd; Emiliano Spezi; Dimitris Visvikis; Habib Zaidi; Assen S Kirov Journal: Med Phys Date: 2017-05-18 Impact factor: 4.071
Authors: Judith van Loon; Marco H M Janssen; Michel Ollers; Hugo J W L Aerts; Ludwig Dubois; Monique Hochstenbag; Anne-Marie C Dingemans; Roy Lalisang; Boudewijn Brans; Bert Windhorst; Guus A van Dongen; Hartmuth Kolb; James Zhang; Dirk De Ruysscher; Philippe Lambin Journal: Eur J Nucl Med Mol Imaging Date: 2010-04-06 Impact factor: 9.236
Authors: Wouter van Elmpt; James Hamill; Judson Jones; Dirk De Ruysscher; Philippe Lambin; Michel Ollers Journal: Eur J Nucl Med Mol Imaging Date: 2011-01-11 Impact factor: 9.236
Authors: Virendra Kumar; Yuhua Gu; Satrajit Basu; Anders Berglund; Steven A Eschrich; Matthew B Schabath; Kenneth Forster; Hugo J W L Aerts; Andre Dekker; David Fenstermacher; Dmitry B Goldgof; Lawrence O Hall; Philippe Lambin; Yoganand Balagurunathan; Robert A Gatenby; Robert J Gillies Journal: Magn Reson Imaging Date: 2012-08-13 Impact factor: 2.546
Authors: Erik Roelofs; Lucas Persoon; Sebastiaan Nijsten; Wolfgang Wiessler; André Dekker; Philippe Lambin Journal: Radiother Oncol Date: 2013-02-05 Impact factor: 6.280
Authors: Erik Roelofs; André Dekker; Vincenzo Valentini; Philippe Lambin; Elisa Meldolesi; Ruud G P M van Stiphout Journal: Radiother Oncol Date: 2013-12-03 Impact factor: 6.280
Authors: M Brambilla; R Matheoud; C Basile; C Bracco; I Castiglioni; C Cavedon; M Cremonesi; S Morzenti; F Fioroni; M Giri; F Botta; F Gallivanone; E Grassi; M Pacilio; E De Ponti; M Stasi; S Pasetto; S Valzano; D Zanni Journal: Comput Math Methods Med Date: 2015-05-19 Impact factor: 2.238