| Literature DB >> 18206964 |
Abstract
The downregulation of gene expression by miRNAs and siRNAs is a complex process involving both translational repression and accelerated mRNA turnover, each of which appears to occur by multiple mechanisms. Moreover, under certain conditions, miRNAs are also capable of activating translation. A variety of cellular proteins have been implicated in these regulatory mechanisms, yet their exact roles remain largely unresolved.Mesh：
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Year: 2008 PMID： 18206964 DOI： 10.1016/j.molcel.2007.12.010
Source DB: PubMed Journal: Mol Cell ISSN： 1097-2765 Impact factor: 17.970