| Literature DB >> 18205171 |
Anna C Need1, Deborah K Attix, Jill M McEvoy, Elizabeth T Cirulli, Kristen N Linney, Ana Patricia Wagoner, Curtis E Gumbs, Ina Giegling, Hans-Jürgen Möller, Clyde Francks, Pierandrea Muglia, Allen Roses, Greg Gibson, Mike E Weale, Dan Rujescu, David B Goldstein.
Abstract
It was recently suggested that the Kibra polymorphism rs17070145 has a strong effect on multiple episodic memory tasks in humans. We attempted to replicate this using two cohorts of European genetic origin (n = 319 and n = 365). We found no association with either the original SNP or a set of tagging SNPs in the Kibra gene with multiple verbal memory tasks, including one that was an exact replication (Auditory Verbal Learning Task, AVLT). These results suggest that Kibra does not have a strong and general effect on human memory. Copyright 2008 Wiley-Liss, Inc.Entities:
Mesh：
Substances：
Year: 2008 PMID： 18205171 DOI： 10.1002/ajmg.b.30658
Source DB: PubMed Journal: Am J Med Genet B Neuropsychiatr Genet ISSN： 1552-4841 Impact factor: 3.568