Literature DB >> 18202685

Obstacles and opportunities in new drug development.

K I Kaitin1.   

Abstract

Mesh：

Substances：

Year:  2008        PMID： 18202685     DOI： 10.1038/sj.clpt.6100462

Source DB:  PubMed          Journal:  Clin Pharmacol Ther        ISSN： 0009-9236            Impact factor:   6.875


× No keyword cloud information.
  15 in total

1.  A virtual national laboratory for reengineering clinical translational science.

Authors:  David M Dilts; Daniel Rosenblum; William M Trochim
Journal:  Sci Transl Med       Date:  2012-01-25       Impact factor: 17.956

2.  The societal benefit of nonprofit biotechnology companies.

Authors:  Rena M Conti
Journal:  Clin Adv Hematol Oncol       Date:  2008-05

3.  Increased levels of urinary phenylacetylglycine associated with mitochondrial toxicity in a model of drug-induced phospholipidosis.

Authors:  Lucette Doessegger; Georg Schmitt; Barbara Lenz; Holger Fischer; Götz Schlotterbeck; Elke-Astrid Atzpodien; Hans Senn; Laura Suter; Miklos Csato; Stefan Evers; Thomas Singer
Journal:  Ther Adv Drug Saf       Date:  2013-06

Review 4.  Induced pluripotent stem cells as a model for accelerated patient- and disease-specific drug discovery.

Authors:  I Gunaseeli; M X Doss; C Antzelevitch; J Hescheler; A Sachinidis
Journal:  Curr Med Chem       Date:  2010       Impact factor: 4.530

5.  Nonprofit biomedical companies.

Authors:  R M Conti; D O Meltzer; M J Ratain
Journal:  Clin Pharmacol Ther       Date:  2008-08       Impact factor: 6.875

6.  Laboratory tests in the clinical risk management of potential drug-drug interactions: a cross-sectional study using drug-dispensing data from 100 Dutch community pharmacies.

Authors:  Arjen F J Geerts; Fred H P De Koning; Peter A G M De Smet; Wouter W Van Solinge; Toine C G Egberts
Journal:  Drug Saf       Date:  2009       Impact factor: 5.606

7.  Big data and artificial intelligence (AI) methodologies for computer-aided drug design (CADD).

Authors:  Jai Woo Lee; Miguel A Maria-Solano; Thi Ngoc Lan Vu; Sanghee Yoon; Sun Choi
Journal:  Biochem Soc Trans       Date:  2022-02-28       Impact factor: 4.919

8.  Traditional chinese medicine-based network pharmacology could lead to new multicompound drug discovery.

Authors:  Jian Li; Cheng Lu; Miao Jiang; Xuyan Niu; Hongtao Guo; Li Li; Zhaoxiang Bian; Na Lin; Aiping Lu
Journal:  Evid Based Complement Alternat Med       Date:  2012-12-17       Impact factor: 2.629

9.  Exploring the inhibitory potentials of Momordica charantia bioactive compounds against Keap1-Kelch protein using computational approaches.

Authors:  Temitope Isaac Adelusi; Misbaudeen Abdul-Hammed; Mukhtar Oluwaseun Idris; Oyedele Qudus Kehinde; Ibrahim Damilare Boyenle; Ukachi Chiamaka Divine; Ibrahim Olaide Adedotun; Ajayi Ayodeji Folorunsho; Oladipo Elijah Kolawole
Journal:  In Silico Pharmacol       Date:  2021-06-25

Review 10.  ADDME--Avoiding Drug Development Mistakes Early: central nervous system drug discovery perspective.

Authors:  Katya Tsaioun; Michel Bottlaender; Aloise Mabondzo
Journal:  BMC Neurol       Date:  2009-06-12       Impact factor: 2.474
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.