Literature DB >> 18202397

Differential regulation of anaphase promoting complex/cyclosome substrates by the spindle assembly checkpoint in Saccharomyces cerevisiae.

Brice E Keyes1, Christopher M Yellman, Daniel J Burke.   

Abstract

The anaphase promoting complex (APC) targets proteins for degradation to promote progression through the cell cycle. Here we show that Clb5, an APCCdc20 substrate, is degraded when the spindle checkpoint is active, while other APCCdc20 substrates are stabilized, suggesting that APCCdc20 inhibition by the spindle checkpoint is substrate specific.

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Year:  2008        PMID： 18202397      PMCID： PMC2206106          DOI： 10.1534/genetics.107.083642

Source DB:  PubMed          Journal:  Genetics        ISSN： 0016-6731            Impact factor:   4.562


  17 in total

1.  Testing cyclin specificity in the exit from mitosis.

Authors:  M D Jacobson; S Gray; M Yuste-Rojas; F R Cross
Journal:  Mol Cell Biol       Date:  2000-07       Impact factor: 4.272

Review 2.  The spindle assembly and spindle position checkpoints.

Authors:  Daniel J Lew; Daniel J Burke
Journal:  Annu Rev Genet       Date:  2003       Impact factor: 16.830

Review 3.  The anaphase promoting complex/cyclosome: a machine designed to destroy.

Authors:  Jan-Michael Peters
Journal:  Nat Rev Mol Cell Biol       Date:  2006-08-09       Impact factor: 94.444

Review 4.  The ubiquitin-proteasome pathway in cell cycle control.

Authors:  Steven I Reed
Journal:  Results Probl Cell Differ       Date:  2006

5.  CDC20 and CDH1: a family of substrate-specific activators of APC-dependent proteolysis.

Authors:  R Visintin; S Prinz; A Amon
Journal:  Science       Date:  1997-10-17       Impact factor: 47.728

6.  Spindle checkpoint regulates Cdc20p stability in Saccharomyces cerevisiae.

Authors:  Jing Pan; Rey-Huei Chen
Journal:  Genes Dev       Date:  2004-06-15       Impact factor: 11.361

7.  CLB5: a novel B cyclin from budding yeast with a role in S phase.

Authors:  C B Epstein; F R Cross
Journal:  Genes Dev       Date:  1992-09       Impact factor: 11.361

8.  CLB5 and CLB6, a new pair of B cyclins involved in DNA replication in Saccharomyces cerevisiae.

Authors:  E Schwob; K Nasmyth
Journal:  Genes Dev       Date:  1993-07       Impact factor: 11.361

9.  Assaying the spindle checkpoint in the budding yeast Saccharomyces cerevisiae.

Authors:  Christopher M Yellman; Daniel J Burke
Journal:  Methods Mol Biol       Date:  2004

10.  Anaphase-promoting complex/cyclosome-dependent proteolysis of human cyclin A starts at the beginning of mitosis and is not subject to the spindle assembly checkpoint.

Authors:  S Geley; E Kramer; C Gieffers; J Gannon; J M Peters; T Hunt
Journal:  J Cell Biol       Date:  2001-04-02       Impact factor: 10.539
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  4 in total

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4.  Multiple mechanisms determine the order of APC/C substrate degradation in mitosis.

Authors:  Dan Lu; Jennifer Y Hsiao; Norman E Davey; Vanessa A Van Voorhis; Scott A Foster; Chao Tang; David O Morgan
Journal:  J Cell Biol       Date:  2014-10-06       Impact factor: 10.539
  4 in total

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