Literature DB >> 18199739

Humoral immune responses of tuberculosis patients in Brazil indicate recognition of Mycobacterium tuberculosis MPT-51 and GlcB.

Cristina Melo Cardoso Almeida1, Arioldo C Vasconcelos, André Kipnis, Ana Lúcia Andrade, Ana Paula Junqueira-Kipnis.   

Abstract

The humoral responses to recombinant MPT-51 and GlcB was determined by using an enzyme-linked immunosorbent assay. Levels of immunoglobulin M (IgM) against MPT-51 and IgG against GlcB were higher among tuberculosis (TB) patients than among control individuals. When the MPT-51 and GlcB assays were combined, 90.8% specificity and 75.5% sensitivity were observed. MPT-51 and GlcB were recognized in the humoral responses of Brazilian TB patients.

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Year:  2008        PMID： 18199739      PMCID： PMC2268274          DOI： 10.1128/CVI.00359-07

Source DB:  PubMed          Journal:  Clin Vaccine Immunol        ISSN： 1556-679X


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