Literature DB >> 1819692

Paf-acether in human skin.

Y Denizot1, L Michel, J Benveniste, A Meybeck, Y Thomas, L Dubertret.   

Abstract

Paf is a phospholipid mediator present in human skin which induces inflammatory events, such as neutrophil infiltration and increased vascular permeability. Recent data suggest that cutaneous cells, such as fibroblasts and keratinocytes, produce paf and that paf is released during allergic cutaneous reactions. It is tempting to speculate that paf may contribute to the development of various skin disorders with acute and chronic skin inflammation. Paf antagonists may help in bringing answers to this hypothesis and may offer new prospects for the treatment of cutaneous inflammatory diseases.

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Year:  1991        PMID： 1819692     DOI： 10.1007/BF02536508

Source DB:  PubMed          Journal:  Lipids        ISSN： 0024-4201            Impact factor:   1.880


  17 in total

1.  Association of platelet-activating factor with primary acquired cold urticaria.

Authors:  K E Grandel; R S Farr; A A Wanderer; T C Eisenstadt; S I Wasserman
Journal:  N Engl J Med       Date:  1985-08-15       Impact factor: 91.245

2.  Structural identification of platelet activating factor in psoriatic scale.

Authors:  A I Mallet; F M Cunningham
Journal:  Biochem Biophys Res Commun       Date:  1985-01-16       Impact factor: 3.575

3.  Antihypertensive activity of an alkyl ether analog of phosphatidylcholine.

Authors:  M L Blank; F Snyder; L W Byers; B Brooks; E E Muirhead
Journal:  Biochem Biophys Res Commun       Date:  1979-10-29       Impact factor: 3.575

4.  Accumulation of eosinophils in response to intracutaneous PAF-acether and allergens in man.

Authors:  E Henocq; B B Vargaftig
Journal:  Lancet       Date:  1986-06-14       Impact factor: 79.321

5.  Platelet-activating factor. A potent chemotactic and chemokinetic factor for human eosinophils.

Authors:  A J Wardlaw; R Moqbel; O Cromwell; A B Kay
Journal:  J Clin Invest       Date:  1986-12       Impact factor: 14.808

6.  Platelet-activating factor. Evidence for 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine as the active component (a new class of lipid chemical mediators).

Authors:  C A Demopoulos; R N Pinckard; D J Hanahan
Journal:  J Biol Chem       Date:  1979-10-10       Impact factor: 5.157

7.  Inflammatory characteristics of platelet activating factor (PAF-acether) in human skin.

Authors:  C B Archer; C P Page; W Paul; J Morley; D M MacDonald
Journal:  Br J Dermatol       Date:  1984-01       Impact factor: 9.302

8.  Inhibitory effect of oral cetirizine on in vivo antigen-induced histamine and PAF-acether release and eosinophil recruitment in human skin.

Authors:  L Michel; C De Vos; J P Rihoux; C Burtin; J Benveniste; L Dubertret
Journal:  J Allergy Clin Immunol       Date:  1988-07       Impact factor: 10.793

9.  Interleukin 1 stimulates platelet-activating factor production in cultured human endothelial cells.

Authors:  F Bussolino; F Breviario; C Tetta; M Aglietta; A Mantovani; E Dejana
Journal:  J Clin Invest       Date:  1986-06       Impact factor: 14.808

10.  Human keratinocytes contain mRNA indistinguishable from monocyte interleukin 1 alpha and beta mRNA. Keratinocyte epidermal cell-derived thymocyte-activating factor is identical to interleukin 1.

Authors:  T S Kupper; D W Ballard; A O Chua; J S McGuire; P M Flood; M C Horowitz; R Langdon; L Lightfoot; U Gubler
Journal:  J Exp Med       Date:  1986-12-01       Impact factor: 14.307
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