PURPOSE: To investigate the effects of various degrees of diffuse fatty infiltration of the liver on portal vein blood flow with Doppler sonography. METHODS: One hundred forty subjects were examined with color and spectral Doppler sonography. The subjects were divided into 4 groups of 35 subjects each according to the degree (normal, grade 1, grade 2 and grade 3) of hepatic fatty infiltration assessed on gray-scale images. The portal vein pulsatility index (VPI) and time-averaged mean flow velocity (MFV) were calculated for each subject. VPI was calculated as (peak maximum velocity - peak minimum velocity) / peak maximum velocity. RESULTS: VPI and MFV values were, respectively, 0.32 +/- 0.06 and 16.8 +/- 2.6 cm/second in the normal group, 0.27 +/- 0.07 and 14.2 +/- 2.2 cm/second in the group with grade 1 fatty infiltration, 0.22 +/- 0.06 and 12.2 +/- 1.8 cm/second in the group with grade 2 fatty infiltration, and 0.18 +/- 0.04 and 10.8 +/- 1.5 cm/second in the group with grade 3 fatty infiltration. There was a negative inverse correlation between the grade of fatty infiltration and both VPI (f = 55.3, p < 0.001) and MFV (f = 43.9, p < 0.001). CONCLUSION: The pulsatility index and mean velocity of the portal vein blood flow decrease as the severity of fatty infiltration increases. (Copyright) 2007 Wiley Periodicals, Inc.
PURPOSE: To investigate the effects of various degrees of diffuse fatty infiltration of the liver on portal vein blood flow with Doppler sonography. METHODS: One hundred forty subjects were examined with color and spectral Doppler sonography. The subjects were divided into 4 groups of 35 subjects each according to the degree (normal, grade 1, grade 2 and grade 3) of hepatic fatty infiltration assessed on gray-scale images. The portal vein pulsatility index (VPI) and time-averaged mean flow velocity (MFV) were calculated for each subject. VPI was calculated as (peak maximum velocity - peak minimum velocity) / peak maximum velocity. RESULTS: VPI and MFV values were, respectively, 0.32 +/- 0.06 and 16.8 +/- 2.6 cm/second in the normal group, 0.27 +/- 0.07 and 14.2 +/- 2.2 cm/second in the group with grade 1 fatty infiltration, 0.22 +/- 0.06 and 12.2 +/- 1.8 cm/second in the group with grade 2 fatty infiltration, and 0.18 +/- 0.04 and 10.8 +/- 1.5 cm/second in the group with grade 3 fatty infiltration. There was a negative inverse correlation between the grade of fatty infiltration and both VPI (f = 55.3, p < 0.001) and MFV (f = 43.9, p < 0.001). CONCLUSION: The pulsatility index and mean velocity of the portal vein blood flow decrease as the severity of fatty infiltration increases. (Copyright) 2007 Wiley Periodicals, Inc.
Authors: Masoud Baikpour; Arinc Ozturk; Manish Dhyani; Nathaniel D Mercaldo; Theodore T Pierce; Joseph R Grajo; Anthony E Samir Journal: AJR Am J Roentgenol Date: 2020-01-15 Impact factor: 3.959
Authors: Georgi Kirovski; Doris Schacherer; Hella Wobser; Hanna Huber; Christoph Niessen; Catrin Beer; Jürgen Schölmerich; Claus Hellerbrand Journal: Int J Clin Exp Med Date: 2010-07-15
Authors: Luis I Cortínez; Brian J Anderson; Nick H G Holford; Valentina Puga; Natalia de la Fuente; Hernán Auad; Sandra Solari; Fidel A Allende; Mauricio Ibacache Journal: Eur J Clin Pharmacol Date: 2015-09-26 Impact factor: 2.953
Authors: Luuk J Rijzewijk; Rutger W van der Meer; Mark Lubberink; Hildo J Lamb; Johannes A Romijn; Albert de Roos; Jos W Twisk; Robert J Heine; Adriaan A Lammertsma; Johannes W A Smit; Michaela Diamant Journal: Diabetes Date: 2010-08-06 Impact factor: 9.461