Literature DB >> 18188834

Gender differences in the prediction of 5-year outcome in first episode psychosis.

Maria Mattsson1, Lena Flyckt, Gunnar Edman, Håkan Nyman, Johan Cullberg, Yvonne Forsell.   

Abstract

OBJECTIVE: To examine gender differences in prediction of long-term outcome in first episode psychosis (FEP).
METHOD: Eighty-one male and 72 female FEP patients were compared regarding the sensitivity and specificity of the Predictive Rating Scale (PRS). The contributions of pre-admission clinical and socio-demographic characteristics to a poor 5-year outcome were analysed for males and females separately. Gender differences in the relations between predictors and outcome were examined using the equality of correlation comparing correlation coefficients.
RESULTS: The sensitivity of the PRS was significantly better for males than for females. The following items: 'the highest Global Assessment of Functioning (GAF) the year before first admission < or =70' and 'GAF at first admission < or =30' explained most of the variance of a poor 5-year outcome for males, whereas for females the corresponding items were 'the highest educational level is compulsory school', 'living with parents' and 'contact with friends < or =2-3 times/month'. When the PRS was adapted assigning a weight of two to the item 'the highest educational level is compulsory school' for females, the sensitivity increased.
CONCLUSION: This study revealed that the predictors for poor outcome differ between male and female patients with FEP.

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Year:  2007        PMID: 18188834      PMCID: PMC6878358          DOI: 10.1002/mpr.228

Source DB:  PubMed          Journal:  Int J Methods Psychiatr Res        ISSN: 1049-8931            Impact factor:   4.035


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