| Literature DB >> 18187748 |
Omar Tliba1, Yassine Amrani, Reynold A Panettieri.
Abstract
Airway smooth muscle (ASM) plays a central role in regulating bronchomotor tone in patients with asthma. New evidence, however, suggests that ASM may also orchestrate and perpetuate airway inflammation by promoting the recruitment, activation, and trafficking of inflammatory cells in the airways. This review addresses the immunomodulatory function of ASM and highlights how such function may have therapeutic implications in the management of asthma.Entities:
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Year: 2008 PMID: 18187748 DOI: 10.1378/chest.07-0262
Source DB: PubMed Journal: Chest ISSN: 0012-3692 Impact factor: 9.410