Literature DB >> 18184860

PDGF-C is a proinflammatory cytokine that mediates renal interstitial fibrosis.

Frank Eitner1, Eva Bücher, Claudia van Roeyen, Uta Kunter, Song Rong, Claudia Seikrit, Luigi Villa, Peter Boor, Linda Fredriksson, Gudrun Bäckström, Ulf Eriksson, Arne Ostman, Jürgen Floege, Tammo Ostendorf.   

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Year:  2008        PMID： 18184860      PMCID： PMC2396746          DOI： 10.1681/ASN.2007030290

Source DB:  PubMed          Journal:  J Am Soc Nephrol        ISSN： 1046-6673            Impact factor:   10.121


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  22 in total

1.  Expression analysis of PDGF-C in adult and developing mouse tissues.

Authors:  Karin Aase; Alexandra Abramsson; Linda Karlsson; Christer Betsholtz; Ulf Eriksson
Journal:  Mech Dev       Date:  2002-01       Impact factor: 1.882

2.  Angiogenesis stimulated by PDGF-CC, a novel member in the PDGF family, involves activation of PDGFR-alphaalpha and -alphabeta receptors.

Authors:  Renhai Cao; Ebba Bråkenhielm; Xuri Li; Kristian Pietras; Johan Widenfalk; Arne Ostman; Ulf Eriksson; Yuhai Cao
Journal:  FASEB J       Date:  2002-10       Impact factor: 5.191

3.  Over-expression of PDGF-C using a lung specific promoter results in abnormal lung development.

Authors:  Ying Zhuo; Gary W Hoyle; Bin Shan; Dawn R Levy; Joseph A Lasky
Journal:  Transgenic Res       Date:  2006-07-09       Impact factor: 2.788

4.  A chemokine receptor CCR-1 antagonist reduces renal fibrosis after unilateral ureter ligation.

Authors:  Hans-Joachim Anders; Volker Vielhauer; Michael Frink; Yvonne Linde; Clemens D Cohen; Simone M Blattner; Matthias Kretzler; Frank Strutz; Matthias Mack; Hermann-Josef Gröne; James Onuffer; Richard Horuk; Peter J Nelson; Detlef Schlöndorff
Journal:  J Clin Invest       Date:  2002-01       Impact factor: 14.808

5.  Inhibition of platelet-derived growth factor receptors reduces interstitial hypertension and increases transcapillary transport in tumors.

Authors:  K Pietras; A Ostman; M Sjöquist; E Buchdunger; R K Reed; C H Heldin; K Rubin
Journal:  Cancer Res       Date:  2001-04-01       Impact factor: 12.701

6.  PDGF-C is a new protease-activated ligand for the PDGF alpha-receptor.

Authors:  X Li; A Pontén; K Aase; L Karlsson; A Abramsson; M Uutela; G Bäckström; M Hellström; H Boström; H Li; P Soriano; C Betsholtz; C H Heldin; K Alitalo; A Ostman; U Eriksson
Journal:  Nat Cell Biol       Date:  2000-05       Impact factor: 28.824

7.  Expression of a novel PDGF isoform, PDGF-C, in normal and diseased rat kidney.

Authors:  Frank Eitner; Tammo Ostendorf; Claudia Van Roeyen; Masashi Kitahara; Xuri Li; Karin Aase; Hermann-Josef Gröne; Ulf Eriksson; Jürgen Floege
Journal:  J Am Soc Nephrol       Date:  2002-04       Impact factor: 10.121

8.  Platelet-derived growth factor C (PDGF-C), a novel growth factor that binds to PDGF alpha and beta receptor.

Authors:  D G Gilbertson; M E Duff; J W West; J D Kelly; P O Sheppard; P D Hofstrand; Z Gao; K Shoemaker; T R Bukowski; M Moore; A L Feldhaus; J M Humes; T E Palmer; C E Hart
Journal:  J Biol Chem       Date:  2001-04-10       Impact factor: 5.157

9.  PDGF-C expression in the developing and normal adult human kidney and in glomerular diseases.

Authors:  Frank Eitner; Tammo Ostendorf; Matthias Kretzler; Clemens D Cohen; Ulf Eriksson; Hermann-Josef Gröne; Jürgen Floege
Journal:  J Am Soc Nephrol       Date:  2003-05       Impact factor: 10.121

Review 10.  Chemokines and chemokine receptors in renal pathology.

Authors:  Stephan Segerer; Charles E Alpers
Journal:  Curr Opin Nephrol Hypertens       Date:  2003-05       Impact factor: 2.894
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  37 in total

Review 1.  TGF-β1 → SMAD/p53/USF2 → PAI-1 transcriptional axis in ureteral obstruction-induced renal fibrosis.

Authors:  Rohan Samarakoon; Jessica M Overstreet; Stephen P Higgins; Paul J Higgins
Journal:  Cell Tissue Res       Date:  2011-06-04       Impact factor: 5.249

2.  Targeting endothelium-pericyte cross talk by inhibiting VEGF receptor signaling attenuates kidney microvascular rarefaction and fibrosis.

Authors:  Shuei-Liong Lin; Fan-Chi Chang; Claudia Schrimpf; Yi-Ting Chen; Ching-Fang Wu; Vin-Cent Wu; Wen-Chih Chiang; Frank Kuhnert; Calvin J Kuo; Yung-Ming Chen; Kwan-Dun Wu; Tun-Jun Tsai; Jeremy S Duffield
Journal:  Am J Pathol       Date:  2011-02       Impact factor: 4.307

Review 3.  Renal interstitial fibrosis: mechanisms and evaluation.

Authors:  Alton B Farris; Robert B Colvin
Journal:  Curr Opin Nephrol Hypertens       Date:  2012-05       Impact factor: 2.894

4.  PDGF-C mediates glomerular capillary repair.

Authors:  Peter Boor; Claudia R C van Roeyen; Uta Kunter; Luigi Villa; Eva Bücher; Bernd Hohenstein; Christian P M Hugo; Ulf Eriksson; Simon C Satchell; Peter W Mathieson; Frank Eitner; Jürgen Floege; Tammo Ostendorf
Journal:  Am J Pathol       Date:  2010-05-20       Impact factor: 4.307

Review 5.  Targeting CTGF, EGF and PDGF pathways to prevent progression of kidney disease.

Authors:  Helena M Kok; Lucas L Falke; Roel Goldschmeding; Tri Q Nguyen
Journal:  Nat Rev Nephrol       Date:  2014-10-14       Impact factor: 28.314

Review 6.  [New approaches in progressive kidney diseases].

Authors:  P Boor
Journal:  Pathologe       Date:  2012-11       Impact factor: 1.011

Review 7.  Renal fibrosis: novel insights into mechanisms and therapeutic targets.

Authors:  Peter Boor; Tammo Ostendorf; Jürgen Floege
Journal:  Nat Rev Nephrol       Date:  2010-09-14       Impact factor: 28.314

Review 8.  Pharmacological targeting of the PDGF-CC signaling pathway for blood-brain barrier restoration in neurological disorders.

Authors:  Sebastian A Lewandowski; Linda Fredriksson; Daniel A Lawrence; Ulf Eriksson
Journal:  Pharmacol Ther       Date:  2016-08-12       Impact factor: 12.310

Review 9.  Angiogenic cytokines in renovascular disease: do they have potential for therapeutic use?

Authors:  Alejandro R Chade; Nicholas Stewart
Journal:  J Am Soc Hypertens       Date:  2013-02-19

10.  VEGF-independent angiogenic pathways induced by PDGF-C.

Authors:  Xuri Li; Anil Kumar; Fan Zhang; Chunsik Lee; Yang Li; Zhongshu Tang; Pachiappan Arjuna
Journal:  Oncotarget       Date:  2010-08
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