Literature DB >> 18183936

Targeted antibodies in dairy-based products.

Lennart Hammarström1, Carina Krüger Weiner.   

Abstract

Bovine colostrum contains immunoglobulins that provide the newborn calf with protection against microbial infections until its own immune system matures. The concentration of antibodies in colostrum against pathogens can be raised by immunizing cows with pathogens or their antigens. Bovine colostrum-based immune milk products have proven efficacy in prophylaxis and treatment against various infectious diseases in humans such as diarrheal diseases caused by various pathogens like E. coli and rotavirus. Still, future attempts are needed to increase the yield and the concentration of antibodies in order to achieve full protection.

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Year:  2008        PMID： 18183936     DOI： 10.1007/978-0-387-74087-4_13

Source DB:  PubMed          Journal:  Adv Exp Med Biol        ISSN： 0065-2598            Impact factor:   2.622


  6 in total

1.  Hyperimmune bovine colostrum as a low-cost, large-scale source of antibodies with broad neutralizing activity for HIV-1 envelope with potential use in microbicides.

Authors:  Marit Kramski; Rob J Center; Adam K Wheatley; Jonathan C Jacobson; Marina R Alexander; Grant Rawlin; Damian F J Purcell
Journal:  Antimicrob Agents Chemother       Date:  2012-06-04       Impact factor: 5.191

2.  Alleviation of insulin resistance and liver damage by oral administration of Imm124-E is mediated by increased Tregs and associated with increased serum GLP-1 and adiponectin: results of a phase I/II clinical trial in NASH.

Authors:  Meir Mizrahi; Yehudit Shabat; Ami Ben Ya'acov; Gadi Lalazar; Tomer Adar; Victor Wong; Brian Muller; Grant Rawlin; Yaron Ilan
Journal:  J Inflamm Res       Date:  2012-12-20

3.  Prevention and treatment of influenza with hyperimmune bovine colostrum antibody.

Authors:  Wy Ching Ng; Victor Wong; Brian Muller; Grant Rawlin; Lorena E Brown
Journal:  PLoS One       Date:  2010-10-26       Impact factor: 3.240

Review 4.  Effects of Bovine Immunoglobulins on Immune Function, Allergy, and Infection.

Authors:  Laurien H Ulfman; Jeanette H W Leusen; Huub F J Savelkoul; John O Warner; R J Joost van Neerven
Journal:  Front Nutr       Date:  2018-06-22

5.  Colostrum from cows immunized with a veterinary vaccine against bovine rotavirus displays enhanced in vitro anti-human rotavirus activity.

Authors:  Andrea Civra; Alessandra Altomare; Rachele Francese; Manuela Donalisio; Giancarlo Aldini; David Lembo
Journal:  J Dairy Sci       Date:  2019-04-10       Impact factor: 4.034

6.  A Double-Blind, Randomized Intervention Study on the Effect of a Whey Protein Concentrate on E. coli-Induced Diarrhea in a Human Infection Model.

Authors:  Laurien H Ulfman; Joyce E L Schloesser; Guus A M Kortman; Maartje van den Belt; Elly Lucas-van de Bos; Joris Roggekamp; R J Joost van Neerven; Mojtaba Porbahaie; Els van Hoffen; Alwine F M Kardinaal
Journal:  Nutrients       Date:  2022-03-12       Impact factor: 5.717
  6 in total

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