Literature DB >> 1818343

Anti-allergic effect of bryonolic acid from Luffa cylindrica cell suspension cultures.

S Tanaka1, C Uno, M Akimoto, M Tabata, C Honda, W Kamisako.   

Abstract

The anti-allergic activity of bryonolic acid (1) isolated from the cultured cells of Luffa cylindrica L. (Cucurbitaceae) was compared with that of glycyrrhetinic acid (2), the aglycone of glycyrrhizin from licorice. Compound 1, when administered to rats intraperitoneally at a dose of 600 mg/kg, inhibited homologous passive cutaneous anaphylaxis more strongly than 2 at the same dose. Compound 1 also significantly inhibited delayed hypersensitivity in mice which could not be inhibited by 2. In contrast to 2, 1 showed not only little toxicity but no visible side effects on mice, without impairing the activity of the hepatic enzyme (4,5 beta-dihydrocortisone:NADP+ delta 4-oxidoreductase) involved in steroid catabolism.

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Year:  1991        PMID： 1818343     DOI： 10.1055/s-2006-960199

Source DB:  PubMed          Journal:  Planta Med        ISSN： 0032-0943            Impact factor:   3.352


  9 in total

1.  Intracellular distribution of the hydrophobic triterpene, bryonolic acid, in cultured cells of Luffa cylindrica L.

Authors:  J Shimakura; H J Cho; S Tanaka; H Fukui; W Kamisako; M Tabata
Journal:  Plant Cell Rep       Date:  1993-03       Impact factor: 4.570

2.  Bryonolic acid: a large-scale isolation and evaluation of heme oxygenase 1 expression in activated macrophages.

Authors:  Emily C Barker; Tonibelle N Gatbonton-Schwager; Yong Han; Jennifer E Clay; John J Letterio; Gregory P Tochtrop
Journal:  J Nat Prod       Date:  2010-06-25       Impact factor: 4.050

3.  Bryonolic acid transcriptional control of anti-inflammatory and antioxidant genes in macrophages in vitro and in vivo.

Authors:  Tonibelle N Gatbonton-Schwager; John J Letterio; Gregory P Tochtrop
Journal:  J Nat Prod       Date:  2012-02-16       Impact factor: 4.050

Review 4.  Principle of Hot and Cold and Its Clinical Application in Latin American and Caribbean Medicines.

Authors:  Carlos A Vásquez-Londoño; Luisa F Cubillos-Cuadrado; Andrea C Forero-Ozer; Paola A Escobar-Espinosa; David O Cubillos-López; Daniel F Castaño-Betancur
Journal:  Adv Exp Med Biol       Date:  2021       Impact factor: 2.622

5.  Anti-tumor agents 255: novel glycyrrhetinic acid-dehydrozingerone conjugates as cytotoxic agents.

Authors:  Jin Tatsuzaki; Masahiko Taniguchi; Kenneth F Bastow; Kyoko Nakagawa-Goto; Susan L Morris-Natschke; Hideji Itokawa; Kimiye Baba; Kuo-Hsiung Lee
Journal:  Bioorg Med Chem       Date:  2007-06-14       Impact factor: 3.641

6.  Luffa cylindrica suppresses development of Dermatophagoides farinae-induced atopic dermatitis-like skin lesions in Nc/Nga mice.

Authors:  Hyekyung Ha; Hye-Sun Lim; Mee-Young Lee; In-Sik Shin; Woo Young Jeon; Jung-Hoon Kim; Hyeun Kyoo Shin
Journal:  Pharm Biol       Date:  2014-10-20       Impact factor: 3.503

7.  In Vitro and in Vivo Inhibitory Effects of Glycyrrhetinic Acid in Mice and Human Cytochrome P450 3A4.

Authors:  Qiao-Li Lv; Gui-Hua Wang; Shu-Hui Chen; Lei Hu; Xue Zhang; Guo Ying; Chong-Zhen Qin; Hong-Hao Zhou
Journal:  Int J Environ Res Public Health       Date:  2015-12-25       Impact factor: 3.390

Review 8.  Mapping metabolome changes in Luffa aegyptiaca Mill fruits at different maturation stages via MS-based metabolomics and chemometrics.

Authors:  Amal A Maamoun; Radwa H El-Akkad; Mohamed A Farag
Journal:  J Adv Res       Date:  2019-10-24       Impact factor: 10.479

Review 9.  Glycyrrhizic acid in the treatment of liver diseases: literature review.

Authors:  Jian-yuan Li; Hong-yan Cao; Ping Liu; Gen-hong Cheng; Ming-yu Sun
Journal:  Biomed Res Int       Date:  2014-05-13       Impact factor: 3.411
  9 in total

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