Literature DB >> 18182326

Genomics of reproduction in nematodes: prospects for parasite intervention?

Alasdair J Nisbet1, Pauline A Cottee, Robin B Gasser.   

Abstract

Understanding reproductive processes in parasitic nematodes has the potential to lead to the informed design of new anthelmintics and control strategies. Little is known, however, about the molecular mechanisms underlying sex determination, gametogenesis and reproductive physiology for most parasitic nematodes. Together with comparative analyses of data for the free-living nematode Caenorhabditis elegans, molecular investigations are beginning to provide insights into the processes involved in reproduction and development in parasitic nematodes. Here, we review recent developments, focusing on technological aspects and on molecules associated with sex-specific differences in adult nematodes.

Entities:  

Mesh：

Substances：

Year:  2008        PMID： 18182326     DOI： 10.1016/j.pt.2007.12.001

Source DB:  PubMed          Journal:  Trends Parasitol        ISSN： 1471-4922


  8 in total

Review 1.  Cracking the nodule worm code advances knowledge of parasite biology and biotechnology to tackle major diseases of livestock.

Authors:  Rahul Tyagi; Anja Joachim; Bärbel Ruttkowski; Bruce A Rosa; John C Martin; Kymberlie Hallsworth-Pepin; Xu Zhang; Philip Ozersky; Richard K Wilson; Shoba Ranganathan; Paul W Sternberg; Robin B Gasser; Makedonka Mitreva
Journal:  Biotechnol Adv       Date:  2015-05-27       Impact factor: 14.227

2.  First transcriptomic analysis of the economically important parasitic nematode, Trichostrongylus colubriformis, using a next-generation sequencing approach.

Authors:  Cinzia Cantacessi; Makedonka Mitreva; Bronwyn E Campbell; Ross S Hall; Neil D Young; Aaron R Jex; Shoba Ranganathan; Robin B Gasser
Journal:  Infect Genet Evol       Date:  2010-08-06       Impact factor: 3.342

3.  Transcriptome analyses reveal protein and domain families that delineate stage-related development in the economically important parasitic nematodes, Ostertagia ostertagi and Cooperia oncophora.

Authors:  Esley Heizer; Dante S Zarlenga; Bruce Rosa; Xin Gao; Robin B Gasser; Jessie De Graef; Peter Geldhof; Makedonka Mitreva
Journal:  BMC Genomics       Date:  2013-02-22       Impact factor: 3.969

4.  Gender-associated genes in filarial nematodes are important for reproduction and potential intervention targets.

Authors:  Ben-Wen Li; Amy C Rush; Dao-Jun Jiang; Makedonka Mitreva; Sahar Abubucker; Gary J Weil
Journal:  PLoS Negl Trop Dis       Date:  2011-01-25

5.  A deep sequencing approach to comparatively analyze the transcriptome of lifecycle stages of the filarial worm, Brugia malayi.

Authors:  Young-Jun Choi; Elodie Ghedin; Matthew Berriman; Jacqueline McQuillan; Nancy Holroyd; George F Mayhew; Bruce M Christensen; Michelle L Michalski
Journal:  PLoS Negl Trop Dis       Date:  2011-12-13

6.  Transcriptome profiling of the fifth-stage larvae of Angiostrongylus cantonensis by next-generation sequencing.

Authors:  Lian-chen Wang; Kuang-yao Chen; Shih-hsin Chang; Li-yu Chung; Ruei-chi Richie Gan; Chien-ju Cheng; Petrus Tang
Journal:  Parasitol Res       Date:  2013-07-05       Impact factor: 2.289

Review 7.  Helminth genomics: The implications for human health.

Authors:  Paul J Brindley; Makedonka Mitreva; Elodie Ghedin; Sara Lustigman
Journal:  PLoS Negl Trop Dis       Date:  2009-10-26

8.  Transcription profiling reveals stage- and function-dependent expression patterns in the filarial nematode Brugia malayi.

Authors:  Ben-Wen Li; Zhengyuan Wang; Amy C Rush; Makedonka Mitreva; Gary J Weil
Journal:  BMC Genomics       Date:  2012-05-14       Impact factor: 3.969
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.